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4794151332E1A022038TANGGUNG JAWAB MARKETPLACE TERHADAP KONSUMEN ATAS
TIDAK TERPENUHINYA PENGIRIMAN BARANG BERDASARKAN
UNDANG-UNDANG NOMOR 8 TAHUN 1999 TENTANG
PERLINDUNGAN KONSUMEN
(Studi Putusan Nomor 553 K/PDT.SUS-BPSK/2025 jo.
Putusan Nomor 50/PDT.SUS-BPSK/2024/PN IDM)		Transaksi melalui marketplace memberikan kemudahan bagi konsumen, namun
dalam praktiknya masih ditemukan permasalahan berupa tidak terpenuhinya
pengiriman barang yang berpotensi menimbulkan kerugian. Penelitian ini mengkaji
tanggung jawab marketplace terhadap konsumen serta bentuk perlindungan hukum
berdasarkan Undang-Undang Nomor 8 Tahun 1999 tentang Perlindungan
Konsumen (UUPK) dengan studi pada Putusan Mahkamah Agung Republik
Indonesia Nomor 553 K/Pdt.Sus-BPSK/2025 jo. Putusan Pengadilan Negeri
Indramayu Nomor 50/Pdt.Sus-BPSK/2024/PN Idm. Metode penelitian yang
digunakan adalah yuridis normatif melalui pendekatan perundang-undangan dan
pendekatan kasus, dengan data sekunder yang diperoleh dari studi kepustakaan dan
dianalisis secara kualitatif. Hasil penelitian menunjukkan bahwa PT Tokopedia
dapat dikualifikasikan sebagai pelaku usaha karena mengendalikan mekanisme
pembayaran, alur informasi status pesanan, serta penanganan komplain dan refund.
Namun, pemulihan hak konsumen tidak diberikan sesuai tenggat waktu
sebagaimana ketentuan Pasal 19 UUPK sehingga perlindungan preventif melalui
mekanisme internal platform tidak terpenuhi. Pemenuhan hak konsumen pada
akhirnya diperoleh melalui penyelesaian sengketa di BPSK dan peradilan.		Transactions conducted through marketplaces provide convenience for consumers;
however, in practice, problems such as the non-fulfillment of goods delivery are still
found and may cause consumer losses. This study examines the liability of
marketplaces toward consumers and the forms of legal protection based on Law
Number 8 of 1999 on Consumer Protection (UUPK), with a case study of the
Supreme Court Decision of the Republic of Indonesia Number 553 K/Pdt.SusBPSK/2025 in conjunction with the Indramayu District Court Decision Number
50/Pdt.Sus-BPSK/2024/PN Idm. The research method employed is normative
juridical research using a statutory approach and a case approach, with secondary
data obtained through library research and analyzed qualitatively. The results show
that PT Tokopedia can be classified as a business actor because it controls the
payment mechanism, the flow of order status information, as well as complaint
handling and refund procedures. However, the restoration of consumer rights was
not provided within the time limit as stipulated in Article 19 of the UUPK, so
preventive protection through the platform’s internal mechanism was not fulfilled.
Ultimately, the fulfillment of consumer rights was obtained through dispute
resolution at the Consumer Dispute Settlement Agency (BPSK) and the courts.
4794251334J1E019045THE IMPLEMENTATION OF GENERATING INTERACTION BETWEEN SCHEMATA AND TEXT (GIST) STRATEGY IN NARRATIVE TEXTS FOR 11th GRADE STUDENTS OF SMAN 4 PURWOKERTOUtami, Faidah Fitri, 2025. The Implementation of Generating Interaction Between Schemata and Text (GIST) Strategy in Narrative Texts for 11th Grade Students of SMAN 4 Purwokerto. Skripsi. Pembimbing I: Erna Wardani, S.Pd., M.Hum. Pembimbing II: Nisa Roiyasa, S.Pd., M.Ed., TESOL. Ketua Penguji Eksternal: Slamet Riyadi, S.S., M. Pd. Penguji Eksternal: Novita Pri Andini, S.Pd., M.Pd. Kementerian Pendidikan Tinggi, Sains, dan Teknologi. Universitas Jenderal Soedirman. Fakultas Ilmu Budaya. Jurusan Pendidikan Bahasa. Program Studi S1 Pendidikan Bahasa Inggris. Purwokerto.
Penelitian ini membahas implementasi strategi Generating Interaction Between Schemata and Text (GIST) dalam pengajaran teks naratif di SMA N 4 Purwokerto. Penelitian ini menggunakan strategi Generating Interaction Between Schemata and Text (GIST) yang dikemukakan oleh Cunningham (1982). Teori ini berfokus pada membantu siswa meringkas informasi kompleks menjadi 20 kata atau kurang dengan mengaktifkan pengetahuan sebelumnya (skema) untuk lebih memahami ide utama. Penelitian ini juga menggabungkan teori dari Maulina, Drajati, & Zainnuri (2022), Saepudin, Sulistyorini, dan Utanto (2019), dan Slameto (2010) dalam Komang Sriponi (2021) untuk mengevaluasi bagaimana siswa merespons strategi ini. Tujuan penelitian ini adalah untuk mengetahui bagaimana implementasi dan respons siswa terkait penggunaan strategi ini.
Penelitian ini menggunakan metode kualitatif deskriptif, melibatkan 36 siswa dan satu guru bahasa Inggris. Data dikumpulkan melalui observasi, kuesioner, wawancara, dan dokumen. Temuan menunjukkan bahwa strategi GIST diimplementasikan secara efektif melalui tiga langkah utama: pra-membaca, membaca, dan pasca-membaca. Selanjutnya, siswa melaporkan respons positif terhadap strategi tersebut. Statistik deskriptif dari hasil kuesioner siswa menunjukkan bahwa 100% siswa menyukai strategi tersebut dan merasa strategi tersebut meningkatkan pemahaman membaca mereka. Lebih lanjut, 97% siswa menganggap GIST menarik dan menyatakan keinginan untuk terus menggunakannya, sementara 94% antusias dalam meringkas dan merasa lebih terlibat di kelas. Sekitar 86% siswa melaporkan merasa lebih terlibat, fokus, dan percaya diri dalam kemampuan membaca mereka. Kesimpulannya, implementasi strategi GIST sangat cocok untuk teks naratif, secara efektif meningkatkan keterlibatan siswa dan memenuhi kebutuhan pemahaman siswa.
Utami, Faidah Fitri, 2025. The Implementation of Generating Interaction Between Schemata and Text (GIST) Strategy in Narrative Texts for 11th Grade Students of SMAN 4 Purwokerto. Thesis. Supervisor I: Erna Wardani, S.Pd., M.Hum. Supervisor II: Nisa Roiyasa, S.Pd., M.Ed., TESOL. Chief External Examiner: Slamet Riyadi, S.S., M. Pd. External Examiner: Novita Pri Andini, S.Pd., M.Pd. Ministry of Higher Education, Science, and Technology, Jenderal Soedirman University, Faculty of Humanities, Department of Language Education, English Language Education Study Program, Purwokerto.
This research discusses the implementation of the Generating Interaction Between Schemata and Text (GIST) strategy in teaching narrative text at SMA N 4 Purwokerto. This research uses the Generating Interaction Between Schemata and Text (GIST) strategy proposed by Cunningham (1982). This theory focuses on helping students summarize complex information into 20 words or fewer by activating prior knowledge (schemata) to better understand main ideas. This research also combines theories from Maulina, Drajati, & Zainnuri (2022), Saepudin, Sulistyorini, and Utanto (2019), and Slameto (2010) in Komang Sriponi (2021) to evaluate how students respond to this strategy. The purpose of this research is to determine how the implementation and students' responses regarding the use of this strategy.
A descriptive qualitative method was used in this research, involving 36 students and one English teacher. Data were collected through observations, questionnaires, interviews, and documents. The findings indicated that the GIST strategy was implemented effectively across three main steps: pre-reading, reading, and post-reading. Furthermore, students reported positive responses to the strategy. Descriptive statistics from the student questionnaire results showed that 100% of students liked the strategy and felt it improved their reading comprehension. Furthermore, 97% of students found GIST engaging and expressed a desire to continue using it, while 94% were enthusiastic about summarizing and felt more engaged in class. Approximately 86% of students reported feeling more engaged, focused, and confident in their reading abilities. In conclusion, the implementation of the GIST strategy is very suitable for narrative text, effectively increasing student engagement and meeting students' comprehension needs.
4794351323I1B022095Hubungan Pengetahuan dan Self-Efficacy dengan Sikap Pertolongan Pertama Trauma Muskuloskeletal pada Karang Taruna di Desa Cihonje Kecamatan Gumelar Kabupaten BanyumasLatar Belakang: Trauma muskuloskeletal merupakan penyebab utama years lived with disability (YLDs) di dunia, yang sering terjadi pada korban longsor yang selamat. Kondisi ini memerlukan pertolongan pertama yang cepat dan tepat untuk mencegah perburukan lebih lanjut. Keberhasilan pertolongan pertama dipengaruhi oleh pengetahuan, self-efficacy, dan sikap petugas pertolongan pertama. Penelitian ini bertujuan untuk menganalisis hubungan antara pengetahuan dan self-efficacy dengan sikap anggota Karang Taruna dalam memberikan pertolongan pertama trauma muskuloskeletal.

Metode: Penelitian ini merupakan studi kuantitatif dengan analisis korelasi menggunakan pendekatan cross sectional. Sampel dalam penelitian ini terdiri dari 73 orang menggunakan teknik consecutive sampling dengan kriteria inklusi dan eksklusi. Analisis data dilakukan menggunakan analisis univariat dan bivariat. Uji korelasi yang digunakan adalah uji korelasi nonparametrik Spearman Rank.

Hasil: Hasil penelitian menunjukkan 49,3% memiliki pengetahuan baik, 80,8% memiliki self-efficacy kategori sedang, dan 98,6% memiliki sikap positif terhadap pertolongan pertama trauma muskuloskeletal. Uji korelasi pengetahuan dan sikap menunjukkan tidak ada hubungan yang signifikan dengan p=0,424 (p>0,05). Adapun uji korelasi self-efficacy dengan sikap menunjukkan hubungan yang signifikan dengan p=0,000 (p<0,05) dengan kekuatan korelasi kuat (r=0,631).

Kesimpulan: Tidak terdapat hubungan antara pengetahuan dengan sikap pertolongan pertama trauma muskuloskeletal, sedangkan terdapat hubungan yang kuat antara self-efficacy dengan sikap pertolongan pertama trauma muskuloskeletal.		Background: Musculoskeletal trauma is the leading cause of years lived with disability (YLDs) worldwide, commonly occurring in landslides survivors. This condition requires prompt and appropriate first aid to prevent further deterioration. The success of first aid is influenced by the knowledge, self-efficacy, and attitude of the first responder. This study aims to analyze the relationship between knowledge and self-efficacy with the attitudes of Karang Taruna members in providing first aid for musculoskeletal trauma.

Methods: This study is a quantitative study with correlational analysis using a cross-sectional approach. The sample in this study consisted of 73 people using consecutive sampling technique with inclusion and exclusion criteria. Data analysis was performed using univariate and bivariate analysis. The correlation test used was the nonparametric Spearman's rank correlation test.

Results: The results showed that 49.3% had good knowledge, 80.8% had moderate self-efficacy, and 98.6% had a positive attitude towards first aid for musculoskeletal trauma. The correlation test between knowledge and attitude showed no significant relationship with p=0.424 (p>0.05). The correlation test between self-efficacy and attitude showed a significant relationship with p=0.000 (p<0.05) with a strong correlation strength (r=0.631).

Conclusion: There was no relationship between knowledge and attitudes toward musculoskeletal trauma first aid, while there was a strong relationship between self-efficacy and attitudes toward musculoskeletal trauma first aid.
4794451341I1B022016Hubungan antara Efikasi Diri dengan Stres Kerja pada Perawat di Ruang Onkologi RSUD Prof. Dr. Margono SoekarjoLatar belakang: Perawat onkologi menghadapi tuntutan kerja tinggi, kompleksitas tindakan, serta beban emosional dalam merawat pasien kanker, kondisi ini berisiko menimbulkan stres kerja. Efikasi diri, yaitu keyakinan individu terhadap kemampuan dirinya dalam menghadapi tugas dan tekanan, berperan penting dalam menjaga kesejahteraan psikologis serta mendukung performa kerja. Penelitian ini bertujuan untuk mengetahui hubungan antara efikasi diri dengan stres kerja pada perawat di ruang onkologi RSUD Prof. Dr. Margono Soekarjo
Metodologi: Penelitian ini menggunakan desain kuantitatif dengan pendekatan cross-sectional. Sampel penelitian berjumlah 43 perawat yang bekerja di ruang onkologi dan dipilih menggunakan teknik total sampling. Pengumpulan data dilakukan menggunakan kuesioner NPSES dan ENSS. Analisis data dilakukan menggunakan uji korelasi Rank Spearman.
Hasil Penelitian: Hasil penelitian menunjukkan bahwa sebagian besar perawat memiliki tingkat efikasi diri pada kategori sedang (65,1%) dan tingkat stres kerja pada kategori ringan (53,5%). Hasil uji korelasi Spearman menunjukkan terdapat hubungan yang signifikan antara efikasi diri dan stres kerja dengan nilai p-value = 0,038 dan koefisien korelasi r = -0,317, yang menunjukkan hubungan negatif dengan kekuatan lemah menuju sedang.
Kesimpulan: Terdapat hubungan yang signifikan antara efikasi diri dan stres kerja pada perawat di ruang onkologi RSUD Prof. Dr. Margono Soekarjo, di mana semakin tinggi efikasi diri perawat maka semakin rendah tingkat stres kerja yang dialami. Peningkatan efikasi diri perawat perlu menjadi perhatian sebagai salah satu strategi dalam manajemen stres kerja di lingkungan onkologi.
Background: Oncology nurses face high work demands, complexity of actions, and the emotional burden of caring for cancer patients, these conditions risk causing work stress. Self-efficacy, which is an individual's belief in his or her ability to deal with tasks and pressures, plays an important role in maintaining psychological well-being and supporting work performance. This study aims to determine the relationship between self-efficacy and work stress in nurses in the oncology room of Prof. Dr. Margono Soekarjo Hospital
Methodology: This study uses a quantitative design with a cross-sectional approach. The research sample amounted to 43 nurses working in the oncology room and were selected using the total sampling technique. Data collection was carried out using NPSES and ENSS questionnaires. Data analysis was carried out using the Rank Spearman correlation test.
Study Results: The results showed that most nurses had a level of self-efficacy in the moderate category (65.1%) and a level of work stress in the mild category (53.5%). The results of the Spearman correlation test showed a significant relationship between self-efficacy and work stress with a p-value = 0.038 and a correlation coefficient of r = -0.317, indicating a negative relationship with weak to moderate strength.
Conclusion: There is a significant relationship between self-efficacy and work stress in nurses in the oncology room of Prof. Dr. Margono Soekarjo Hospital, where the higher the self-efficacy of nurses, the lower the level of work stress experienced. Improving nurses' self-efficacy needs to be a concern as one of the strategies in work stress management in the oncology environment.
4794551335I1B022039Pengaruh Kangaroo Mother Care (KMC) Intermiten Terhadap Stres Ibu dengan Bayi Berat Lahir Rendah (BBLR) di Ruang Perawatan NeonatusLatar Belakang: Kondisi bayi berat badan lahir rendah (BBLR) secara klinis memerlukan perawatan intensif yang memicu pemisahan fisik dan peningkatan stres pada ibu. Intervensi kangaroo mother care (KMC) intermiten merupakan upaya memperbaiki respon psikologis serta memfasilitasi kedekatan ibu dan bayi. Penelitian ini bertujuan mengetahui pengaruh KMC intermiten terhadap tingkat stres ibu dengan bayi BBLR di ruang neonatus.
Metodologi: Desain penelitian ini adalah quasi-experimental dengan pendekatan one group pretest-posttest design without control group. Sampel berjumlah 35 responden yang diambil dengan teknik convenience sampling di RSUD Prof. Dr. Margono Soekarjo. Tingkat stres diukur sebelum dan sesudah intervensi KMC selama 3 hari. Analisis data menggunakan uji non-parametrik Wilcoxon Signed-Ranks Test.
Hasil Penelitian: Karakteristik responden menunjukkan rata-rata usia ibu 31,06 tahun, mayoritas berpendidikan SLTA (40%), IRT (77,1%), multipara (60%), persalinan SC (88,6%), dan usia gestasi preterm (97,1%). Bayi didominasi kategori BBLR (65,7%). Hasil uji Wilcoxon menunjukkan p-value 0,001 (p < 0,05), yang berarti terdapat perbedaan signifikan skor stres ibu sebelum dan sesudah dilakukan intervensi. Nilai median skor stres ibu menurun sebesar 44,8% (dari 116 menjadi 64), dengan 97,1% responden mengalami penurunan skor stres ibu setelah intervensi.
Kesimpulan: Intervensi Kangaroo Mother Care (KMC) intermiten terbukti mampu menurunkan tingkat stres pada ibu dengan bayi BBLR secara nyata. Penerapan metode ini perlu penguatan edukasi dan motivasi berkelanjutan dari perawat agar ibu dapat melakukan KMC secara konsisten untuk mendukung kesehatan mental.
Background: Clinically, low birth weight (LBW) infants require intensive care, which causes physical separation and increased stress for mothers. Intermittent kangaroo mother care (KMC) is an intervention aimed at improving psychological responses and facilitating closeness between mothers and infants. This study aims to determine the effect of intermittent KMC on the stress levels of mothers with LBW infants in the neonatal ward.
Methodology: This study used a quasi-experimental design with a one-group pretest-posttest approach without a control group. The sample consisted of 35 respondents selected using convenience sampling at Prof. Dr. Margono Soekarjo General Hospital. Stress levels were measured before and after the 3-day KMC intervention. Data analysis was performed using the Wilcoxon Signed-Ranks Test.
Research Resulut: Respondent characteristics showed that the average age of mothers was 31.06 years, the majority had a high school education (40%), were housewives (77.1%), multiparous (60%), had a cesarean section (88.6%), and had a preterm gestational age (97.1%). Babies were predominantly in the low birth weight category (65.7%). The Wilcoxon test results showed a p-value of 0.001 (p < 0.05), which means that there was a significant difference in the mothers' stress scores before and after the intervention. The median value of the mothers' stress scores decreased by 44.8% (from 116 to 64), with 97.1% of respondents experiencing a decrease in their stress scores after the intervention.
Conclusion: Intermittent Kangaroo Mother Care (KMC) intervention has been proven to significantly reduce stress levels in mothers with LBW babies. The implementation of this method requires continuous education and motivation from nurses so that mothers can perform KMC consistently to support mental health.
4794651337I1B022070Hubungan Pengetahuan dan Motivasi dengan Perilaku Pencegahan Osteoporosis pada Wanita Premenopause di Desa Ledug
Latar Belakang: Osteoporosis merupakan gangguan sistemik pada tulang yang ditandai berkurangnya massa tulang sehingga meningkatkan risiko fraktur. Pada periode premenopause terjadi peningkatan risiko osteoporosis sehingga diperlukan perilaku pencegahan sedini mungkin. Tujuan penelitian ini adalah untuk menganalisis hubungan antara pengetahuan dan motivasi dengan perilaku pencegahan osteoporosis pada wanita premenopause di Desa Ledug.

Metodologi: Penelitian kuantitatif korelasional dengan pendekatan cross sectional. Sampel pada penelitian ini adalah 125 wanita premenopause dengan teknik pengambilan sampel purposive cluster sampling. Instrumen yang digunakan Menopause Rating Scale (MRS), Osteoporosis Knowledge Assessment Tools (OKAT), Treatment Self-Regulation Questionnaire (TSRQ), dan instrumen perilaku pencegahan osteoporosis. Hipotesis diuji menggunakan uji Spearman Rank.

Hasil Penelitian: Karakteristik usia responden memiliki nilai median 45, proporsi responden dengan tingkat pendidikan SD dan status tidak bekerja sedikit lebih tinggi dibandingkan kategori lainnya. Median skor pengetahuan 9 (0-18), motivasi 48 (39-64), dan perilaku pencegahan osteoporosis 11 (6-14). Terdapat hubungan antara pengetahuan dan motivasi dengan perilaku pencegahan osteoporosis pada wanita premenopause (p < 0,05).

Kesimpulan: Pengetahuan dan motivasi berhubungan dengan perilaku pencegahan osteoporosis pada wanita premenopause di Desa Ledug. Peneliti lain dapat meneliti lebih lanjut mengenai faktor lain yang memengaruhi perilaku pencegahan osteoporosis pada wanita premenopause.
Background: Osteoporosis is a systemic bone disorder characterized by decreased bone mass, leading to an increases risk of fractures. During premenopausal period, there is an increased risk of osteoporosis, making early preventive behavior essential. This study aimed to analyze the relationship between knowledge and motivation with osteoporosis prevention behaviour among premenopausal women in Ledug Village.

Methodology: This study employed a correlational quantitative design with a cross-sectional approach. A total of 125 premenopausal women were selected using purposive cluster sampling. Data were collected using the Menopause Rating Scale (MRS), Osteoporosis Knowledge Assessment Tools (OKAT), Treatment Self-Regulation Questionnaire (TSRQ), and osteoporosis preventive behavior questionnare. The hypotheses were tested using the Spearman Rank test.

Results: The median age of the respondents was 45 years, Most respondents had elementary-level education and were unemployed. The median scores for knowledge, motivation, and osteoporosis prevention behavior were 9 (0-18), 48 (39-64), and 11 (6-14) respectively. There was a significant association between knowledge and motivation with osteoporosis prevention behaviour among premenopausal women (p < 0,05).

Conclusion: Knowledge and motivation were associated with osteoporosis prevention behaviour among premenopausal women in Ledug Village. Further research is recommended to explore other factors influencing osteoporosis prevention behaviour.
4794751339A1A019065Tingkat Kepuasan Perajin Gula Kelapa Kristal terhadap Kinerja Kemitraan dengan PT. Holos Integra di Kabupaten BanyumasGula kelapa kristal merupakan komoditas unggulan Kabupaten Banyumas yang berorientasi pada pasar nasional dan ekspor, dengan keberlanjutan produksi yang sangat bergantung pada perajin dan efektivitas kemitraan agribisnis. PT. Holos Integra merupakan perusahaan yang menjalin kemitraan dengan perajin gula kelapa kristal organik di wilayah tersebut. Dalam beberapa tahun terakhir terjadi penurunan jumlah perajin mitra yang diikuti oleh penurunan luas lahan, jumlah pohon kelapa produktif, dan volume produksi. Penurunan jumlah mitra dipengaruhi oleh faktor dari sisi perajin dan perusahaan. Dari sisi perajin, keterbatasan ketersediaan nira akibat berkurangnya pohon kelapa produktif, penurunan kapasitas produksi, serta kendala regenerasi mendorong sebagian perajin beralih kemitraan atau profesi lain. Dari sisi perusahaan, penyesuaian jumlah mitra dilakukan sebagai respons terhadap penurunan permintaan pasar dan kebijakan efisiensi produksi. Kondisi tersebut menunjukkan pentingnya tingkat kepuasan perajin terhadap kinerja kemitraan dalam menjaga keberlanjutan kerja sama. Penelitian ini bertujuan untuk mengetahui pelaksanaan kemitraan, menganalisis tingkat kepuasan perajin, serta menilai kesesuaian antara tingkat kepentingan dan kinerja kemitraan PT. Holos Integra.
Penelitian ini menggunakan metode survei yang dilaksanakan di Kabupaten Banyumas, tepatnya di Desa Cirangkong dan Desa Ciwera Kecamatan Gumelar serta Desa Karang Delima Kecamatan Pekuncen. Lokasi penelitian ditentukan secara purposive karena merupakan sentra perajin mitra aktif perusahaan. Responden penelitian berjumlah 35 perajin gula kelapa kristal yang dipilih menggunakan metode purposive sampling dengan kriteria perajin aktif dan terdaftar sebagai mitra PT. Holos Integra. Data primer diperoleh melalui kuesioner berskala Likert, wawancara, dan observasi lapangan, sedangkan data sekunder diperoleh dari studi kepustakaan dan dokumen perusahaan. Analisis data dilakukan secara deskriptif dengan pendekatan Customer Satisfaction Index (CSI) untuk mengukur tingkat kepuasan perajin dan Importance Performance Analysis (IPA) untuk mengevaluasi kesesuaian antara tingkat kepentingan dan kinerja kemitraan.
Hasil penelitian menunjukkan bahwa kemitraan antara perajin dan PT. Holos Integra menerapkan pola inti–plasma, dengan perusahaan berperan dalam pembinaan teknis, pengawasan mutu, sertifikasi organik, dan pemasaran, sedangkan perajin bertanggung jawab terhadap proses produksi sesuai standar perusahaan. Nilai Customer Satisfaction Index (CSI) sebesar 73,86 persen menunjukkan bahwa perajin berada pada kategori puas terhadap kinerja kemitraan. Hasil Importance Performance Analysis (IPA) menunjukkan bahwa sebagian besar atribut kemitraan telah sesuai dengan harapan perajin, sementara beberapa aspek masih memerlukan prioritas perbaikan, meliputi pemerataan peralatan produksi, ketepatan waktu pengambilan produk, respons terhadap perubahan harga pasar, serta perhatian terhadap kesejahteraan perajin. Perbaikan pada aspek tersebut diharapkan dapat meningkatkan kepuasan perajin dan memperkuat keberlanjutan kemitraan.		Granulated coconut sugar was a leading commodity in Banyumas Regency oriented toward national and export markets, with production sustainability highly dependent on artisans and the effectiveness of agribusiness partnerships. PT. Holos Integra was a company that established partnerships with organic granulated coconut sugar artisans in the region. In recent years, a decline occurred in the number of partner artisans, followed by reductions in land area, the number of productive coconut trees, and production volume. The decrease in partner numbers was influenced by factors from both the artisans’ and the company’s perspectives. From the artisans’ side, limited sap availability due to declining productive coconut trees, reduced production capacity, and regeneration constraints encouraged some artisans to shift partnerships or change occupations. From the company’s side, adjustments in the number of partners were implemented in response to declining market demand and production efficiency policies. These conditions indicated the importance of artisans’ satisfaction with partnership performance in maintaining the sustainability of cooperation. This study aimed to examine the implementation of the partnership, analyze artisans’ satisfaction levels, and assess the conformity between the level of importance and partnership performance of PT. Holos Integra.
This study used a survey method conducted in Banyumas Regency, specifically in Cirangkong Village and Ciwera Village of Gumelar District, and Karang Delima Village of Pekuncen District. The research locations were purposively selected because they were centers of active partner artisans of the company. The respondents consisted of 35 granulated coconut sugar artisans selected using purposive sampling, with criteria including active production status and official partnership with PT. Holos Integra. Primary data were collected through Likert-scale questionnaires, interviews, and field observations, while secondary data were obtained from literature studies and company documents. Data analysis was conducted descriptively using the Customer Satisfaction Index (CSI) to measure artisans’ satisfaction levels and Importance Performance Analysis (IPA) to evaluate the conformity between importance levels and partnership performance.
The results showed that the partnership between artisans and PT. Holos Integra applied an nucleus–plasma pattern, in which the company played roles in technical guidance, quality control, organic certification, and marketing, while artisans were responsible for production processes in accordance with company standards. The Customer Satisfaction Index (CSI) value of 73.86 percent indicated that artisans were categorized as satisfied with partnership performance. The Importance Performance Analysis (IPA) results showed that most partnership attributes met artisans’ expectations, while several aspects required priority improvement, including the equitable distribution of production equipment, timeliness of product collection, responsiveness to market price changes, and attention to artisans’ welfare. Improvements in these aspects were expected to enhance artisans’ satisfaction and strengthen the sustainability of the partnership.
4794851338G1B021024Pengaruh Ekstrak Etanol Daun Awar-Awar (Ficus septica Burm. F.) terhadap Biofilm Bakteri Streptococcus sanguinis Penyebab Karies GigiKaries gigi merupakan penyakit progresif kronis akibat produksi asam yang dihasilkan oleh bakteri di dalam rongga mulut. Streptococcus sanguinis merupakan salah satu bakteri koloni primer yang berperan penting dalam pembentukan biofilm yang dapat menyebabkan karies gigi. Chlorhexidine gluconate merupakan agen kemoterapi paling poten dalam mengurangi jumlah plak dalam rongga mulut tetapi dapat memberikan efek samping apabila digunakan dalam jangka panjang. Salah satu alternatif yang dapat digunakan adalah daun awar-awar karena memiliki kandungan flavonoid, alkaloid, saponin, dan tanin yang berpotensi sebagai antibiofilm. Tujuan penelitian adalah mengetahui pengaruh ekstrak etanol daun awar-awar (Ficus septica Burm. F.) terhadap biofilm bakteri S. sanguinis penyebab karies gigi. Jenis penelitian eksperimental laboratoris dengan metode in vitro yang dirancang sebagai posttest-only control group design. Sampel dikelompokan menjadi 7, yaitu ekstrak etanol daun awar-awar konsentrasi 87,5mg/mL, 175mg/mL, 350mg/mL, 700mg/mL, 1.400mg/mL, chlorhexidine gluconate 0,2% sebagai kontrol positif, dan DMSO 10% sebagai kontrol negatif. Metode yang digunakan adalah Microtitter Plate Assay dengan pewarnaan kristal violet 1%. Analisis data menggunakan One-Way Anova dan dilanjut dengan uji Post-Hoc Least Significant Different (LSD). Hasil statistik menunjukkan adanya perbedaaan aktivitas penghambatan dan degradasi yang signifikan (p ≤ 0,05) antar kelompok perlakuan. Persentase penghambatan tertinggi didapatkan pada konsentrasi 350mg/mL dan persentase degradasi tertinggi didapatkan pada konsentrasi 87,5mg/mL. Simpulan penelitian adalah terdapat pengaruh ekstrak etanol daun awar-awar terhadap biofilm bakteri S. sanguinis sehingga berpotensi dijadikan sebagai alternatif obat kumur untuk karies gigi.Dental caries is a chronic progressive disease caused by acid production from oral bacteria. Streptococcus sanguinis is a primary colonizer involved in early dental biofilm formation and contributes to caries development. Chlorhexidine gluconate is widely regarded as an effective chemotherapeutic agent, however its long-term use may cause adverse effects, prompting the need for natural alternative. Ficus septica leaves contain bioactive compounds such as flavonoids, alkaloids, saponins, and tannins, which exhibit potential antibiofilm properties. This study aimed to evaluate the effect of Ficus septica ethanol leaf extract on the biofilm of S. sanguinis associated with dental caries. This experimental laboratory study employed an in vitro posttest-only control group design. Samples were divided into seven groups: Ficus septica ethanol extract at concentrations of 87,5mg/mL, 175mg/mL, 350mg/mL, 700mg/mL, 1.400mg/mL; 0,2% chlorhexidine gluconate as the positive control; and 10% DSMO as the negative control. Biofilm inhibition and degradation were assessed using the Microtitter Plate Assay with 1% crystal violet staining. Data were analyzed using One-Way Anova followed by the Least Significant Difference (LSD) post-hoc test. Statistical analysis revealed significant differences in biofilm inhibition and degradation across treatment groups (p ≤ 0,05). The highest inhibition percentage was observed at the 350mg/mL concentration, while the highest degradation percentage was found at the 87,5mg/mL concentration. Ficus septica ethanol leaf extract demonstrates significant inhibitory and degradative effects on S. sanguinis biofilm, indicating its potential use as a natural alternative mouthwash agent for dental caries prevention.
4794951340A1D021036PENGARUH JAMUR ENTOMOPATOGEN Fusarium oxysporum YANG DIPERBANYAK PADA BEBERAPA MEDIA CAIR TERHADAP MORTALITAS ULAT JAGUNG Spodoptera frugiperdaUlat grayak (Spodoptera frugiperda) merupakan hama utama pada tanaman jagung yang dapat mengakibatkan penurunan produksi. Jamur Fusarium oxysporum berpotensi sebagai agens pengendali hayati karena bersifat patogen terhadap beberapa jenis serangga. Penelitian ini bertujuan untuk mengetahui beberapa media cair, yaitu PDB, air cucian beras, air kelapa, dan limbah cair tahu, terhadap produksi konidia F. oxysporum, mortalitas dan biologi larva, serta aktivitas makan larva S. frugiperda. Penelitian menggunakan Rancangan Acak Kelompok (RAK) non-faktorial dengan empat perlakuan yaitu isolat F. oxysporum diperbanyak pada media PDB sebagai kontrol, air cucian beras, air kelapa, dan limbah cair tahu. Setiap perlakuan diulang enam kali. Data hasil pengamatan dianalisis menggunakan Analysis of Variance (ANOVA) pada taraf kesalahan 5%. Apabila terdapat perbedaan nyata antar perlakuan, dilanjutkan dengan uji Beda Nyata Terkecil (BNT) pada taraf kesalahan 5%. Hasil penelitian menunjukkan bahwa aplikasi jamur tidak berpengaruh nyata terhadap jumlah konidia, mortalitas, perkembangan stadia larva dan fertilitas imago. Perlakuan PDB menghasilkan umur hidup imago dan fekunditas tertinggi, sementara itu perlakuan air cucian beras memberikan umur hidup imago dan fekunditas terendah. Selain itu, perlakuan air cucian beras menghasilkan aktivitas makan larva terendah. Berdasarkan hasil penelitian, jenis media cair mempengaruhi beberapa aspek biologi S. frugiperda, meskipun tidak berpengaruh terhadap mortalitas larva.The fall armyworm (Spodoptera frugiperda) is a major pest of maize that can cause significant yield losses. The fungus Fusarium oxysporum has potential as a biological control agent because it is pathogenic to several insect species. This study aimed to evaluate the effects of several liquid media PDB, rice-washing water, coconut water, and tofu wastewater on conidia production of F. oxysporum, larval mortality and biology, as well as the feeding activity of S. frugiperda larvae. This research used a non-factorial Randomized Block Design (RBD) with four treatments: F. oxysporum propagated in Potato Dextrose Broth (PDB) as the control, rice-washing water, coconut water, and tofu wastewater. Each treatment was replicated six times. Data were analyzed using ANOVA with a significance level of 5%. In cases of significant differences, the analysis continued with a least significant difference (LSD) test with a significance level of 5%. The results showed that the fungal application had no significant effect on conidia density, larval mortality, larval developmental duration, or adult fertility. The PDB treatment produced the longest adult lifespan and the highest fecundity, meanwhile, the rice-washing water treatment resulted in the shortest adult lifespan and the lowest fecundity.. In addition, the rice-washing water treatment also yielded the lowest larval feeding activity. Based on these findings, the type of liquid medium influences several biological aspects of S. frugiperda, although it does not affect larval mortality.
4795051342F1D022048Repertoar Aksi Queer for Palestine di Berlin: Dari Ruang Publik sampai Perlawanan DiskursifPenelitian ini menganalisis repertoar aksi dan perlawanan diskursif Queer for Palestine di Berlin dalam konteks politik Jerman yang represif terhadap solidaritas pro-Palestina. Menggunakan konsep repertoar Charles Tilly dan dengan memperluas analisis melalui konsep kekuasaan Michel Foucault, serta memanfaatkan rentang data 2019–2025, penelitian ini menelaah bagaimana gerakan Queer for Palestine di Berlin merespons pembatasan ruang publik dan kriminalisasi simbol Palestina yang dibingkai sebagai isu keamanan dan ketertiban publik. Dengan metode kualitatif dan pendekatan hermeneutika fenomenologis, penelitian ini menafsirkan tindakan kolektif, simbol, artefak budaya, serta produksi narasi publik yang dihasilkan oleh gerakan tersebut. Hasil penelitian menunjukkan adanya pergeseran repertoar dari aksi jalanan menuju taktik non-konvensional seperti kampanye digital dan ruang budaya alternatif sebagai respons terhadap menyempitnya peluang politik. Secara diskursif, Queer for Palestine di Berlin merekonstruksi identitas queer sebagai identitas anti-kolonial, menentang praktik pinkwashing Israel, dan mengartikulasikan narasi moral yang menghubungkan perjuangan queer dengan pembebasan Palestina. Penelitian ini menunjukkan bahwa meskipun tidak menghasilkan perubahan kebijakan secara langsung, gerakan ini membentuk perlawanan epistemik yang mengganggu narasi negara mengenai queer, keamanan, dan legitimasi politik. Dengan demikian, repertoar aksi Queer for Palestine di Berlin berfungsi sebagai strategi dekolonial untuk mempertahankan ruang resistensi di tengah eskalasi represi negara.This study analyzes the repertoire of actions and discursive resistance of Queer for Palestine in Berlin within the context of Germany's repressive politics toward pro-Palestinian solidarity. Using Charles Tilly's concept of repertoire and expanding the analysis through Michel Foucault's concept of power, as well as utilizing data from 2019–2025, this study examines how the Queer for Palestine movement in Berlin responds to restrictions on public space and the criminalization of Palestinian symbols framed as issues of public security and order. Using qualitative methods and a phenomenological hermeneutic approach, this study interprets the collective actions, symbols, cultural artifacts, and public narratives produced by the movement. The results show a shift in repertoire from street actions to unconventional tactics such as digital campaigns and alternative cultural spaces in response to narrowing political opportunities. Discursively, Queer for Palestine in Berlin reconstructs queer identity as an anti-colonial identity, opposes Israel's pinkwashing practices, and articulates a moral narrative linking queer struggles with Palestinian liberation. This research shows that although it does not directly result in policy change, this movement forms an epistemic resistance that disrupts the state's narratives on queerness, security, and political legitimacy. Thus, the repertoire of Queer for Palestine actions in Berlin functions as a decolonial strategy to maintain spaces of resistance amid escalating state repression.
4795151344G1B022019PERBEDAAN ARAH DAN SUDUT DILASERASI AKAR GIGI MOLAR KETIGA MANDIBULA ANTARA GIGI IMPAKSI DAN NON-IMPAKSI PADA PEMERIKSAAN RADIOGRAF PANORAMIK DI RSGMP UNSOED Latar Belakang. Dilaserasi merupakan kelainan perkembangan gigi yang ditandai dengan adanya
kelengkungan akar ≥20° terhadap sumbu longitudinal gigi. Tujuan. Tujuan penelitian ini adalah untuk mengetahui
perbedaan arah dan sudut dilaserasi gigi molar ketiga mandibula antara gigi impaksi dan non-impaksi pada pemeriksaan
radiograf panoramik di RSGMP Unsoed. Metode. Penelitian ini merupakan studi observasional analitik dengan
pendekatan cross sectional. Sampel terdiri dari 132 unit gigi yang memenuhi kriteria inklusi dan eksklusi. Pengambilan
sampel dilakukan dengan cara purposive sampling. Sampel diklasifikasikan berdasarkan tiga kelompok penelitian,
yaitu impaksi mesioangular (kelompok P1), impaksi vertikal (kelompok P2), dan non-impaksi (kelompok P3).
Pengukuran dilakukan menggunakan software ImageJ. Data arah dilaserasi yang diperoleh dari hasil pengukuran
dianalisis menggunakan uji Chi-Square dan sudut dilaserasi dianalisis menggunakan uji One-Way ANOVA. Hasil. Hasil
penelitian menunjukkan bahwa terdapat perbedaan arah dilaserasi antara kelompok impaksi mesioangular, impaksi
vertikal, dan non-impaksi (p<0,05) dan terdapat perbedaan sudut dilaserasi antara kelompok impaksi mesioangular,
impaksi vertikal, dan non-impaksi (p<0,05). Simpulan. Simpulan dari penelitian ini yaitu terdapat perbedaan arah dan
sudut dilaserasi yang signifikan antara kelompok impaksi mesioangular, impaksi vertikal, dan non-impaksi.
Kata kunci: arah dilaserasi, dilaserasi, impaksi, radiograf panoramik, sudut dilaserasi.
Background. Dilaceration is a developmental anomaly of the tooth characterized by root curvature of ≥20°
relative to the longitudinal axis of the tooth. Purpose. The aim of this study was to determine the differences in the
direction and angle of dilaceration of mandibular third molars between impacted and non-impacted teeth on panoramic
radiographic examination at RSGMP Unsoed. Methods. This study was an analytical observational study with a cross
sectional approach. The sample consisted of 132 teeth that met the inclusion and exclusion criteria. Sampling was
carried out using a purposive sampling technique. The samples were classified into three study groups: mesioangular
impaction (group P1), vertical impaction (group P2), and non-impaction (group P3). Measurements were performed
using ImageJ software. The data on dilaceration direction obtained from the measurements were analyzed using the
Chi-Square test, and the dilaceration angle was analyzed using the One-Way ANOVA test. Result. The results showed
significant differences in the direction of dilaceration among the mesioangular impaction, vertical impaction, and non
impaction groups (p<0.05), and significant differences in dilaceration angle among the three groups (p<0.05).
Conclusions. In conclusion, there are significant differences in both the direction and the angle of dilaceration between
mesioangular impaction, vertical impaction, and non-impaction groups.
Keywords: dilaceration angle, dilaceration direction, panoramic radiography, root dilaceration, tooth impaction.
4795251345I1B022011HUBUNGAN DUKUNGAN SOSIAL DAN SELF ESTEEM
DENGAN KECEMASAN IBU HAMIL PRIMIGRAVIDA TRIMESTER III DI KABUPATEN BANYUMAS		Latar Belakang: Kecemasan pada ibu hamil primigravida trimester III sering terjadi menjelang persalinan dan dapat memengaruhi kesehatan ibu dan janin. Dukungan sosial dan self esteem diduga berperan dalam memengaruhi kecemasan. Penelitian ini bertujuan mengetahui hubungan dukungan sosial dan self esteem dengan kecemasan ibu hamil primigravida trimester III di Kabupaten Banyumas.
Metode: Penelitian kuantitatif dengan desain analitik korelasional dan pendekatan cross sectional di wilayah kerja Puskesmas Purwokerto Utara 1, Utara 2, Timur 1, Timur 2, Barat, dan Selatan pada September 2025–Januari 2026. Populasi dalam penelitian ini adalah seluruh ibu hamil primigravida trimester III dengan HPL November 2025–Januari 2026, dengan jumlah sampel 72 responden menggunakan total sampling. Instrumen yang digunakan yaitu Perinatal Anxiety Screening Scale (PASS), Multidimensional Scale of Perceived Social Support (MSPSS), dan Rosenberg Self-Esteem Scale (RSES). Analisis data meliputi analisis univariat dan bivariat dengan uji Pearson.
Hasil: Rerata kecemasan responden sebesar 28,5, dukungan sosial sebesar 67,4, dan self esteem sebesar 19,1. Terdapat hubungan signifikan antara self esteem dengan kecemasan (p = 0,004; p>0,05), namun Tidak terdapat hubungan signifikan antara dukungan sosial dengan kecemasan (p = 0,052; p>0,05).
Kesimpulan: Hasil penelitian membuktikan self esteem memiliki hubungan yang bermakna dengan kecemasan ibu hamil primigravida trimester III, sedangkan dukungan sosial tidak memiliki hubungan yang bermakna dengan kecemasan ibu hamil primigravida trimester III.
Kata Kunci: Dukungan sosial, kecemasan, primigravida, self esteem, trimester III.
Background: Anxiety among primigravida women in the third trimester commonly occurs as childbirth approaches and may affect maternal and fetal health. Social support and self-esteem are factors presumed to influence anxiety. This study aimed to determine the relationship between social support and self-esteem with anxiety among third-trimester primigravida women in Banyumas Regency.
Methods: This quantitative study used an analytical correlational design with a cross-sectional approach conducted in the working areas of Purwokerto Utara 1, Utara 2, Timur 1, Timur 2, Barat, and Selatan Public Health Centers from September 2025 to January 2026. The population consisted of all third-trimester primigravida women with expected delivery dates between November 2025 and January 2026. A total of 72 respondents were selected using total sampling. Data were collected using the Perinatal Anxiety Screening Scale (PASS), the Multidimensional Scale of Perceived Social Support (MSPSS), and the Rosenberg Self-Esteem Scale (RSES). Data analysis included univariate and bivariate analyses using the Pearson test.
Results: The mean anxiety score was 28.5, the mean social support score was 67.4, and the mean self-esteem score was 19.1. There was a significant relationship between self-esteem and anxiety (p = 0.004; p < 0.05), while no significant relationship was found between social support and anxiety (p = 0.052; p > 0.05).
Conclusion: The findings indicate that self-esteem has a significant relationship with anxiety among third-trimester primigravida women, whereas social support does not have a significant relationship with anxiety.
Keywords: Social support, anxiety, primigravida, self-esteem, third trimester.
4795351343G1B022007ANALISIS PERBEDAAN DERAJAT DAN LOKASI DILASERASI AKAR GIGI ANTERIOR DAN PREMOLAR MAKSILA PERMANEN PADA PEMERIKSAAN RADIOGRAF PANORAMIK
DI RSGMP UNSOED
Latar Belakang. Dilaserasi akar merupakan variasi anatomis penting karena memengaruhi perencanaan dan keberhasilan terapi endodontik maupun tindakan bedah. Tujuan. Penelitian ini mengevaluasi perbedaan derajat dan lokasi dilaserasi akar pada insisivus lateral, kaninus, premolar pertama, dan premolar kedua maksila permanen berdasarkan radiograf panoramik di RSGMP Unsoed. Metode. Desain penelitian adalah observasional analitik potong lintang menggunakan 224 radiograf panoramik yang diperoleh melalui metode purposive sampling. Penilaian dilakukan oleh dua pengamat terlatih dengan uji reliabilitas Cohen’s Kappa untuk memastikan konsistensi data. Derajat dilaserasi dikategorikan menjadi mild, moderate, dan severe, sedangkan lokasi kelengkungan ditentukan pada sepertiga koronal, tengah, dan apikal akar. Analisis derajat dilaserasi menggunakan uji Kruskal–Wallis dengan uji lanjut Mann–Whitney U, sedangkan distribusi lokasi kelengkungan dianalisis melalui uji Chi-Square. Hasil. Penelitian menunjukkan bahwa dilaserasi ringan merupakan temuan paling dominan (78,1%) dan kelengkungan paling sering terlokalisasi pada sepertiga apikal akar. Terdapat perbedaan bermakna baik dalam distribusi derajat kelengkungan (p<0,001) maupun pola lokasi kelengkungan (p<0,001) antar kelompok gigi. Insisivus lateral menunjukkan variasi morfologi tertinggi, diikuti kaninus dan premolar, yang menegaskan kompleksitas akar gigi anterior maksila dibandingkan kelompok gigi lain. Simpulan. Penelitian ini adalah variasi derajat dan lokasi dilaserasi akar berbeda antar gigi insisivus lateral, kaninus, premolar pertama, dan premolar kedua maksila permanen dengan dominasi kelengkungan ringan pada sepertiga apikal. Implikasi klinis dari temuan ini adalah perlunya evaluasi radiografik yang cermat sebelum tindakan kedokteran gigi untuk meminimalkan risiko komplikasi dan meningkatkan keberhasilan perawatan.
Kata kunci: analisis morfometri, dilaserasi akar, maksila permanen, radiografi panoramik, variasi morfologi
Background. Root dilaceration is an important anatomical variation as it influences treatment planning and the success of both endodontic therapy and surgical procedures. Objective. This study aimed to evaluate differences in the degree and location of root dilaceration in permanent maxillary lateral incisors, canines, first premolars, and second premolars based on panoramic radiographs at RSGMP Unsoed. Methods. The research design was an analytical cross-sectional study utilizing 224 panoramic radiographs obtained through purposive sampling. Assessments were conducted by two trained observers, and interobserver consistency was verified using Cohen’s Kappa reliability test. The degree of dilaceration was classified as mild, moderate, or severe, while the curvature location was categorized within the coronal, middle, or apical third of the root. Differences in dilaceration degree were analyzed using the Kruskal–Wallis test followed by the Mann–Whitney U test, whereas the distribution of curvature location was evaluated using the Chi-Square test. Results. The findings demonstrated that mild dilaceration was the most dominant observation (78.1%), with curvature most frequently located in the apical third. Significant differences were identified in both dilaceration degree (p<0,001) and curvature location patterns (p<0,001) among the tooth groups. Lateral incisors exhibited the highest morphological variation, followed by canines and premolars, highlighting the complexity of anterior maxillary root anatomy compared to other tooth groups. Conclusion. The degree and location of root dilaceration vary among permanent maxillary lateral incisors, canines, first premolars, and second premolars, with a predominance of mild curvature in the apical third. The clinical implication of these findings underscores the need for careful radiographic evaluation prior to dental procedures to minimize complications and improve treatment outcomes.
Keywords: maxillary permanent teeth, morphological variation, morphometric analysis, root dilaceration, panoramic radiography
4795451333G1A019053Pola Penggunaan Obat Antibiotik dan Simptomatik pada Penderita ISPA di Klinik Pratama SoedirmanLatar Belakang: Infeksi Saluran Pernapasan Atas (ISPA) merupakan salah satu penyakit yang paling sering ditemukan di fasilitas pelayanan kesehatan primer dan menjadi penyebab utama kunjungan pasien. Tingginya angka kejadian ISPA berpotensi meningkatkan penggunaan obat, khususnya antibiotik dan obat simptomatik, yang apabila tidak digunakan secara rasional dapat menimbulkan berbagai permasalahan, termasuk resistensi antibiotik.
Tujuan: Mengetahui pola penggunaan obat antibiotik dan simptomatik pada pasien ISPA di Klinik Pratama Soedirman periode Juli 2024 hingga Juni 2025.
Metode: Penelitian ini merupakan penelitian deskriptif observasional dengan rancangan retrospektif. Data diperoleh dari rekam medis pasien ISPA di Klinik Pratama Soedirman selama periode penelitian. Pengambilan sampel dilakukan menggunakan metode total sampling berdasarkan kriteria inklusi dan eksklusi, dengan jumlah sampel sebanyak 2.863 kasus. Data dianalisis secara deskriptif untuk menggambarkan karakteristik pasien, distribusi diagnosis ISPA, serta pola penggunaan obat antibiotik dan simptomatik.
Hasil: Hasil penelitian menunjukkan bahwa mayoritas pasien ISPA berjenis kelamin perempuan (65,4%) dan berada pada kelompok usia remaja 12–25 tahun (85%). Diagnosis ISPA yang paling banyak ditemukan adalah ISPA nonpesifik (J06) sebesar 51,8%. Antibiotik diresepkan pada 57,5% kasus, dengan golongan cephalosporin (60%) sebagai antibiotik yang paling sering digunakan. Obat simptomatik yang paling banyak diresepkan adalah kortikosteroid. Namun, apabila kandungan obat dalam sediaan kompositum dihitung, antihistamin merupakan golongan obat simptomatik yang paling sering digunakan.
Kesimpulan: Penelitian ini menunjukkan bahwa penggunaan antibiotik pada pasien ISPA di Klinik Pratama Soedirman masih cukup tinggi. Oleh karena itu, diperlukan evaluasi dan penguatan penerapan penggunaan obat yang tepat sesuai pedoman terapi ISPA di fasilitas pelayanan kesehatan primer.		Background: Upper Respiratory Tract Infections (URTIs) are among the most common diseases encountered in primary healthcare facilities and are a major cause of patient visits. The high incidence of URTIs may increase the use of medications, particularly antibiotics and symptomatic drugs, which can lead to irrational use and antibiotic resistance if not properly managed.
Objective: This study aimed to analyze the pattern of antibiotic and symptomatic drug use among URTI patients at Soedirman Primary Clinic from July 2024 to June 2025.
Methods: This study was a descriptive observational study with a retrospective design. Data were collected from the medical records of URTI patients at Soedirman Primary Clinic. Total sampling was applied based on inclusion and exclusion criteria, yielding 2.863 cases. Data were analyzed descriptively to describe patient characteristics, URTI diagnosis distribution, and patterns of antibiotic and symptomatic drug use.
Results: The results show that most URTI patients are female (65.4%) and aged 12–25 years (85%). The most common diagnosis is unspecified URTI (J06), accounting for 51,8% of cases. Antibiotics are prescribed in 57,5% of cases, with cephalosporins (60%) being the most frequently used antibiotic class. Corticosteroids are the most commonly prescribed symptomatic drugs. However, when active ingredients in combination products are considered, antihistamines are the most frequently used symptomatic drug class.
Conclusion: This study indicates that antibiotic use among URTI patients at Soedirman Primary Clinic remains relatively high, highlighting the need to strengthen the implementation of rational drug use in accordance with URTI treatment guidelines in primary healthcare settings.
4795551349G1B022022EFIKASI PATCH MUKOADHESIF EKSTRAK BUNGA TELANG (Clitoria ternatea L.) TERHADAP REEPITELIALISASI PADA PENYEMBUHAN LUKA PASCA EKSTRAKSI GIGI (Studi In Vivo pada Tikus Sprague Dawley)
Latar belakang. Ekstraksi gigi merupakan prosedur yang menyebabkan tereksposnya tulang alveolar, perdarahan, serta luka pada jaringan lunak. Luka pada jaringan akan menginisiasi proses penyembuhan luka. Proses penyembuhan luka dapat dioptimalkan menggunakan kandungan fitokimia dalam bunga telang (Clitoria ternatea L.). Tujuan. Penelitian ini bertujuan untuk mengetahui efikasi patch mukoadhesif ekstrak bunga telang terhadap reepitelialisasi pada penyembuhan luka pasca ekstraksi gigi tikus Sprague dawley. Metode. Penelitian ini merupakan true experimental laboratoris secara in vivo dengan rancangan post test only control group design. Penelitian ini menggunakan 40 sampel tikus dalam 5 kelompok yaitu 3 kelompok perlakuan ekstrak bunga telang 5,1%, 10,21%, dan 15,31% (F1, F2, F3) serta kontrol positif iod gliserin (KP) dan kontrol negatif plasebo (KN) yang diaplikasikan patch mukoadhesif selama 7 dan 14 hari. Jaringan ingiva diambil dan dibuat sediaan histologi dengan pewarnaan HE. Proses reepitelialisasi diamati menggunakan indikator peningkatan ketebalan epitel pada 3 lapang pandang oleh 2 pengamat menggunakan mikroskop dan optilab pada perbesaran 100x kemudian di rata-rata. Data dianalisis menggunakan Two Way ANOVA dilanjutkan Post Hoc LSD. Hasil. Hasil Two Way ANOVA menunjukkan perbedaan signifikan antar kelompok perlakuan dan kelompok kontrol pada durasi 7 dan 14 hari (p<0,05). Hasil uji Post Hoc LSD menunjukkan perbedaan signifikan antar kelompok perlakuan dan kelompok kontrol pada durasi 7 dan 14 hari. Simpulan. Patch mukoadhesif ekstrak bunga telang (Clitoria Ternatea L.) efektif membantu proses reepitelialisasi pada proses penyembuhan luka pasca ekstraksi gigi tikus Sprague dawley dengan konsentrasi 5,1%.
Kata kunci : bunga telang, ekstraksi gigi, patch mukoadhesif, reepitelialisasi.
Background. Tooth extraction involve exposure of the alveolar bone, bleeding, and soft-tissue injury. The injury initiates a wound-healing response. The phytochemical constituents of butterfly pea flower (Clitoria ternatea L.) have been reported that may enhance and accelerate tissue repair. Objective. This study aimed to assess the efficacy of a mucoadhesive patch Clitoria ternatea extract in promoting epithelial thickening during post-extraction wound healing in Sprague dawley rats. Methods. A true experimental in vivo with a post test only control group design. 40 Sprague dawley rats were randomly allocated into 5 groups: 3 treatment groups with 5,1%, 10,21%, and 15,31% consentration of Clitoria ternatea extract (F1, F2, F3), positive control treated with iod glycerin (KP), and negative control or placebo (KN). Each formulation was applied as a mucoadhesive patch for 7 and 14 days. Gingival tissues was taken and processed into stained histological sections with HE stainings, and evaluated for epithelial thickness in 3 fields by two independent observers using a microscope with Optilab at 100× magnification. Mean measurements were analyze using Two-Way ANOVA followed by LSD post-hoc. Results. Two-Way ANOVA demonstrated significant differences across treatment and control groups at both 7 and 14 days (p < 0.05). Post-hoc LSD analysis confirmed significant intergroup differences at both time points. Conclusion: The mucoadhesive patch containing Clitoria ternatea extract effectively enhances epithelial thickness during post extraction wound healing in Sprague dawley rats. The 5,1% extract concentration exhibited the most consistent improvement.
Keywords : Clitoria ternatea, tooth extraction, mucoadhesive patch, reepithelialization.
4795651348G1B022009EFEKTIVITAS PATCH MUKOADHESIF EKSTRAK BUNGA TELANG (Clitoria ternatea) DALAM MENGHAMBAT PERTUMBUHAN BAKTERI Streptococcus mitisLatar belakang. Tingginya prevalensi masalah gigi dan mulut di Indonesia
berkontribusi pada tingginya angka pencabutan gigi. Infeksi bakteri pasca
pencabutan gigi oleh Streptococcus mitis (S. mitis) sering dikaitkan dengan kasus
bakteremia. Patch mukoadhesif ekstrak bunga telang (Clitoria ternatea) 15% dapat
menjadi pengobatan alternatif karena efek antibakterinya. Tujuan. Penelitian ini
bertujuan untuk menentukan efektivitas antibakteri patch mukoadhesif ekstrak
bunga telang (Clitoria ternatea) 15% terhadap pertumbuhan S. mitis secara in vitro
dan in silico. Metode. Penelitian ini merupakan eksperimental laboratoris murni
menggunakan uji difusi cakram Kirby–Bauer dengan kelompok perlakuan yang
mengandung ekstrak bunga telang 15%, kontrol positif ampicilin, dan kontrol
negatif, dilengkapi dengan analisis in silico menggunakan PASS online dan
ADMET. Hasil uji in vitro selanjutnya dianalisis menggunakan uji Kruskall Wallis
dan dilanjutkan uji Mann-Whitney. Hasil. Analisis in silico secara deskriptif pada
senyawa aktif dalam bunga telang menunjukkan prediksi aktivitas antibakteri
(Pa>Pi) pada 12 senyawa. Sebagian besar senyawa memiliki profil farmakokinetik
(ADMET) yang dapat dikembangkan menjadi sediaan patch mukoadhesif, meliputi
permeabilitas, kelarutan, dan lipofilisitas yang mendukung pelepasan senyawa aktif
pada mukosa oral. Hasil uji toksisitas menunjukkan keamanan pada 15 senyawa
pada kategori kelas 4-6. Hasil uji in vitro menunjukkan diameter zona hambat
bakteri rata-rata 33,29±0,47 mm. Analisis statistik menunjukkan perbedaan
bermakna antara kelompok perlakuan dibandingkan dengan kontrol negatif
(p=0,037), sedangkan jika dibandingkan dengan kontrol positif tidak bermakna
(p=0,05). Simpulan. Ekstrak bunga telang berpotensi menjadi alternatif obat
antibakteri yang dapat dikembangkan untuk mencegah kasus infeksi bakteri pasca
pencabutan gigi.		Background. The high prevalence of dental and oral problems in Indonesia
contributes to the high rate of tooth extraction. Post-tooth extraction bacterial
infections by Streptococcus mitis (S. mitis) are often associated with bacteremia. A
15% mucoadhesive patch of Clitoria ternatea flower extract can be an alternative
treatment due to its antibacterial effect. Objective. To determine the antibacterial
effectiveness of a 15% mucoadhesive patch of Clitoria ternatea flower extract
against the growth of S. mitis in vitro and in silico. Method. This study was a
laboratory experiment using the Kirby–Bauer disc diffusion test with treatment
groups containing 15% Clitoria ternatea flower extract, ampicillin positive control,
and negative control, supplemented by in silico analysis using PASS online and
ADMET. The results of the in vitro test were then analyzed using the Kruskall Wallis
test and continued with the Mann-Whitney test. Results. Descriptive in silico
analysis of active compounds in Clitoria ternatea flower showed predicted
antibacterial activity (Pa>Pi) in 12 compounds. Most compounds have
pharmacokinetic profiles (ADMET) suitable for mucoadhesive patch development,
including permeability, solubility, and lipophilicity supporting release in oral
mucosa. Toxicity tests showed safety in 15 compounds within class 4–6. In vitro
tests showed an average bacterial inhibition zone diameter of 33.29 ± 0.47 mm.
Statistical analysis showed a significant difference between treatment groups and
negative control (p = 0.037), but not compared to the positive control (p = 0.05).
Conclusion. Butterfly pea flower extract has the potential as an alternative
antibacterial drug to prevent bacterial infection after tooth extraction.
4795751346G1B022030EFEKTIVITAS PATCH MUKOADHESIF EKSTRAK BUNGA TELANG (Clitoria ternatea) DALAM MENGHAMBAT PERTUMBUHAN BAKTERI Staphylococcus aureusEkstraksi gigi berisiko menimbulkan komplikasi alveolar osteitis yang dapat dipengaruhi oleh aktivitas Staphylococcus aureus melalui fibrinolisis Staphylokinase. Sementara itu, antibiotik konvensional terbatas oleh resistensi dan efek samping sehingga penelitian ini bertujuan mengevaluasi efektivitas patch mukoadhesif ekstrak bunga telang (Clitoria ternatea) 15% sebagai alternatif terapi lokal. Metode penelitian diawali dengan uji in silico (PASS Online, SwissADME, Protox III) untuk memprediksi aktivitas antibakteri, farmakokinetik, dan toksisitas senyawa aktif lalu dilakukan uji in vitro metode difusi agar pada media Mueller–Hinton terhadap Staphylococcus aureus setelah pengujian fisik Patch berbasis natrium karboksimetil selulosa (Na-CMC) dan karbopol. Analisis data dilakukan dengan uji Kruskal–Wallis dan Mann–Whitney menggunakan SPSS versi 27 untuk nilai zona hambat, sedangkan hasil uji lainnya dianalisis secara deskriptif. Hasil menunjukkan 13 dari 16 senyawa memiliki probabilitas aktivitas (Pa) lebih besar dari probabilitas inaktivitas (Pi) untuk efek antibakteri, 9 senyawa memenuhi aturan Lipinski dengan toksisitas rendah (kelas IV–VI), serta zona hambat rata-rata 15,65 ± 0,35 mm (kategori kuat), berbeda signifikan dengan kontrol negatif (0 mm; p = 0,037) dan tidak berbeda signifikan dibandingkan kontrol positif (19,22 ± 0,32 mm; p = 0,050). Kesimpulan dari penelitian ini diketahui bahwa patch mukoadhesif ekstrak bunga telang dengan konsentrasi 15% tidak efektif dalam menghambat Staphylococcus aureus secara in vitro, tetapi tetap berpotensi untuk dikembangkan sebagai terapi pascaekstraksi gigi untuk mengatasi resistensi antibiotik.Tooth extraction may lead to complications such as alveolar osteitis, which can be influenced by Staphylococcus aureus activity through Staphylokinase-mediated fibrinolysis. The use of conventional antibiotics is increasingly limited by antimicrobial resistance and adverse effects, highlighting the need for alternative local therapies. This study aimed to evaluate the effectiveness of a 15% Clitoria ternatea flower extract mucoadhesive patch against Staphylococcus aureus. The study began with in silico analyses using PASS Online, SwissADME, and ProTox-III to predict antibacterial activity, pharmacokinetic properties, and toxicity of active compounds. This was followed by an in vitro agar diffusion assay on Mueller–Hinton agar against Staphylococcus aureus, conducted after physical evaluation of mucoadhesive Patches formulated with sodium carboxymethyl cellulose (Na-CMC) and carbopol. Inhibition zone diameters were analyzed using the Kruskal–Wallis and Mann–Whitney tests with SPSS version 27, while other results were analyzed descriptively. The in silico analysis showed that 13 of 16 compounds had a probability of activity (Pa) greater than the probability of inactivity (Pi) for antibacterial effects. Nine compounds complied with Lipinski’s rule of five and demonstrated low toxicity levels (classes IV–VI). The mean inhibition zone diameter was 15.65 ± 0.35 mm (strong category), significantly different from the negative control (0 mm; p = 0.037) but not significantly different from the positive control (19.22 ± 0.32 mm; p = 0.050). In conclusion, although the 15% Clitoria ternatea mucoadhesive patch was ineffective against Staphylococcus aureus in vitro, it shows potential for further development as a post-tooth extraction therapy addressing antibiotic resistance.
4795851350C1A022080ANALISIS PENGARUH LUAS PANEN PADI, PROPORSI PENGELUARAN PANGAN, DAN NILAI TUKAR PETANI TERHADAP KETAHANAN PANGAN DI PULAU JAWAKetahanan pangan di Pulau Jawa masih menghadapi tantangan, terutama disebabkan oleh masalah produksi beras yang cenderung fluktuatif dan kondisi sosial ekonomi petani yang tidak stabil. Penelitian ini bertujuan untuk menganalisis luas panen padi, proporsi pengeluaran pangan, dan nilai tukar petani (NTP) terhadap keamanan pangan, yang diukur menggunakan Indeks Keamanan Pangan (IKP), di lima provinsi di Jawa dari tahun 2018 hingga 2024. Penelitian ini menggunakan data sekunder dan menerapkan analisis regresi data panel dengan fixed effects model. Hasil analisis menunjukkan bahwa luas panen padi memiliki dampak negatif dan signifikan terhadap ketahanan pangan, sementara nilai tukar petani memiliki dampak positif dan signifikan, namun, proporsi pengeluaran pangan tidak memiliki dampak signifikan terhadap ketahanan pangan. Temuan ini menyarankan bahwa peningkatan produktivitas pertanian harus disertai dengan pengelolaan yang berkelanjutan, serta peningkatan kesejahteraan petani, untuk memperkuat ketahanan pangan nasional.Food security in Java Island still faces challenges, mainly due to the problem of rice production that tends to fluctuate and the unstable socioeconomic conditions of farmers. This study aims to analyze the area of harvest, proportion of food expenditure, and farmer exchange rate (FER) on food security, as measured by the Food Security Index (FSI), in five provinces in Java from 2018 to 2024. This study utilizes secondary data and employs panel data regression analysis with a fixed effects model. The results of the analysis indicate that the rice harvest area has a negative and significant impact on food security, while the farmer's exchange rate has a positive and significant effect, however, the proportion of food expenditure has no significant impact on food security. The findings suggest that increasing agricultural productivity must be accompanied by sustainable management, as well as improving farmers' welfare, to strengthen national food security.
4795951351I1B022062Hubungan Perceived Benefits, Perceived Barriers, dan Self-Efficacy Terhadap Perilaku Pencegahan Gagal Ginjal Kronis Pada RemajaLatar Belakang: Gagal ginjal kronis (GGK) merupakan penyakit tidak menular yang prevalensinya terus meningkat termasuk pada remaja. Kondisi ini berkaitan dengan berbagai perilaku berisiko yang berkaitan dengan gaya hidup tidak sehat. Upaya pencegahan sejak usia remaja penting untuk menurunkan risiko GGK di masa mendatang. Berdasarkan Teori Health Promotion Model, perilaku pencegahan dapat dipengaruhi oleh perceived benefits, perceived barriers, dan self-efficacy. Penelitian ini bertujuan menganalisis hubungan ketiga faktor tersebut dengan perilaku pencegahan GGK pada remaja.

Metode: Penelitian kuantitatif dengan pendekatan cross sectional ini dilakukan pada remaja usia 10–18 tahun di Desa Munjul yang tinggal bersama orang tua. Sampel sebanyak 225 responden dipilih menggunakan teknik purposive sampling dengan alokasi proporsional per RT. Pengumpulan data dilakukan pada September 2025–Januari 2026 menggunakan kuesioner perilaku pencegahan GGK, perceived benefits, perceived barriers, dan self-efficacy yang telah dinyatakan valid dan reliabel. Analisis data menggunakan uji Somers’d.

Hasil: Variabel perceived benefits menunjukkan nilai p = 0,141 dengan r=0,121, sedangkan variabel perceived barriers menunjukkan nilai p < 0,001 dengan r=-0,377, dan variabel self-efficacy menunjukkan nilai p < 0,001 dengan r=0,515 terhadap perilaku pencegahan GGK. Lebih dari dua per tiga responden memiliki perilaku pencegahan GGK, perceived benefits, perceived barriers, dan self-efficacy dalam kategori baik.

Kesimpulan: Perceived benefits tidak menunjukkan hubungan yang bermakna dengan perilaku pencegahan GGK, sedangkan perceived barriers dan self-efficacy menunjukkan hubungan yang bermakna dengan perilaku pencegahan GGK.

Kata kunci: Perceived barriers, Perceived benefits, Perilaku pencegahan GGK, Remaja, Self-efficacy
Background: Chronic kidney disease (CKD) is a non-communicable disease with a continuously increasing prevalence, including among adolescents. This condition is associated with various risk behaviors related to unhealthy lifestyles. Preventive efforts initiated during adolescence are important to reduce the risk of CKD in the future. Based on the Health Promotion Model, preventive behavior may be influenced by perceived benefits, perceived barriers, and self-efficacy. This study aimed to analyze the relationships between these three factors and CKD prevention behavior among adolescents.

Methods: This quantitative cross-sectional study was conducted among adolescents aged 10-18 years in Munjul Village who lived with their parents. A total of 225 respondents were selected through purposive sampling with proportionate allocation in each neighborhood unit. Data were collected from September 2025 to January 2026 using validated and reliable questionnaires on CKD prevention behavior, perceived benefits, perceived barriers, and self-efficacy. Data analysis was performed using the Somers’d test.

Result: The perceived benefits variable showed a p-value of 0,141 with a correlation coefficient r=0,121, whereas the perceived barriers variable showed a p-value of <0,001 with r = -0,377, and self-efficacy showed a p-value of <0,001 with r = 0,515. More than two-thirds of respondents had good levels of CKD prevention behavior, perceived benefits, perceived barriers, and self-efficacy.

Conclusion: Perceived benefits were not significantly associated with CKD preventive behavior, while perceived barriers and self-efficacy showed significant associations with CKD preventive behavior.

Keywords: Adolescents, CKD prevention behavior, Perceived barriers, Perceived benefits, Self-efficacy
4796051353G1B022052Efektivitas Pasta Gigi Nano-Hidroksiapatit Cangkang Keong Sawah Kombinasi Ekstrak Daun Kemangi Terhadap Bakteri Lactobacillus acidophilusLatar Belakang karies gigi merupakan masalah kesehatan gigi dan mulut dengan prevalensi tinggi. Salah satu bakteri penyebab karies gigi adalah Lactobacillus acidophilus. Penelitian ini bertujuan untuk mengetahui efektivitas pasta gigi nano-hidroksiapatit yang disintesis dari cangkang keong sawah dan dikombinasikan dengan ekstrak daun kemangi terhadap pertumbuhan Lactobacillus acidophilus. Metode penelitian eksperimental laboratoris in vitro ini menggunakan metode difusi sumuran dengan kelompok perlakuan berupa pasta gigi ekstrak daun kemangi 5% (P1), pasta gigi nano-hidroksiapatit 10% (P2), pasta gigi nano hidroksiapatit cangkang keong sawah 10% kombinasi ekstrak daun kemangi 5% (P3), pasta gigi komersial berfluoride sebagai kontrol positif (KP), dan akuades steril sebagai kontrol negativ (KN). Parameter penelitian berupa diameter zona hambat pertumbuhan bakteri dianalisis menggunakan uji Kruskal Wallis dan dilanjutkan dengan Post Hoc Mann Whitney. Hasil penelitian menunjukkan bahwa diameter zona hambat paling tinggi terdapat pada kelompok P3 dengan zona hambat sebesar 19,08 mm dan termasuk kategori kuat, diikuti oleh P1, KP, P2, dan KN. Hasil analisis statistik menunjukkan terdapat perbedaan signifikan antara kelompok P1 dengan kelompok P2, P3, KP, dan KN. Simpulan formulasi pasta gigi nano-hidroksiapatit cangkang keong sawah 10% kombinasi ekstrak daun kemangi 5% berpotensi mencegah pertumbuhan bakteri Lactobacillus acidophilus dalam pencegahan karies gigi.Background dental caries remains a major oral health problem with a high prevalence. One of the bacteria that causes dental caries is Lactobacillus acidophilus. This study aimed to determine the effectiveness of toothpaste containing nano-hydroxyapatite synthesized from rice field snail shells combined with basil leaf extract against the growth of Lactobacillus acidophilus. Methods this in vitro experimental laboratory study used the agar well diffusion method with treatment groups consisting of toothpaste containing 5% basil leaf extract (P1), toothpaste containing 10% nano-hydroxyapatite (P2), toothpaste containing 10% nano-hydroxyapatite from rice field snail shells combined with 5% basil leaf extract (P3), commercial fluoride toothpaste as a positive control (KP), and sterile distilled water as a negative control (KN). The research parameter was the diameter of the bacterial growth inhibition zone, which was analyzed using the Kruskal–Wallis test followed by the Post Hoc Mann–Whitney test. Result showed that the highest inhibition zone diameter was found in the P3 group with an inhibition zone of 19.08 mm and classified as strong, followed by P1, KP, P2, and KN. Statistical analysis showed a significant difference between the P1 group and the P2, P3, PC, and NC groups. Conclusion the formulation of toothpaste containing 10% nano-hydroxyapatite from rice field snail shells combined with 5% basil leaf extract has the potential to inhibit the growth of Lactobacillus acidophilus in the prevention of dental caries.