Artikel Ilmiah : P2C022002 a.n. ABARE MUHAMMAD YAKUBU
| NIM | P2C022002 |
|---|---|
| Namamhs | ABARE MUHAMMAD YAKUBU |
| Judul Artikel | The role of heat shock proteins in chicken: Insights into stress adaptation and health |
| Abstrak (Bhs. Indonesia) | This review article aimed to provide readers with a comprehensive understanding of the function of heat shock proteins (HSPs) in chicken physiology, stress response, and overall poultry health. With the increasing challenges faced by the livestock industry, particularly the poultry sector, due to climate change-induced high ambient temperatures, heat stress (HS) has become a critical concern. HS disrupts the thermal balance in poultry, leading to detrimental effects on growth, immune function, and overall health. HSPs play a pivotal role in mitigating the impacts of HS in chickens. These molecular chaperones are involved in protein folding, unfolding, and assembly, and they are classified into several families based on their size, including small molecule HSPs, HSP40, HSP60, HSP70, HSP90, and HSP110. By maintaining cellular homeostasis and promoting stress tolerance, HSPs act as vital guardians in helping chickens cope with HS and its associated consequences. The review synthesized relevant literature to shed light on the importance of HSPs in stress adaptation, cellular homeostasis, and the maintenance of normal cell metabolism in chickens. The adverse effects of HS on chickens include oxidative stress and compromised immune systems, making them more susceptible to infections. So also, HS negatively affects production performance and meat quality in poultry. Understanding the functions of HSPs in chickens offers valuable insights into stress adaptation and health, and could potentially lead to the identification of HSP biomarkers, genetic selection for heat tolerance, investigations into the interplay between HSPs and immune function, and the development of nutritional interventions to enhance HSP activity. By exploring these potential research directions, the review aimed to contribute to the development of novel approaches to mitigate the negative effects of HS on poultry, ultimately improving productivity and animal welfare in a changing climate. |
| Abtrak (Bhs. Inggris) | This review article aimed to provide readers with a comprehensive understanding of the function of heat shock proteins (HSPs) in chicken physiology, stress response, and overall poultry health. With the increasing challenges faced by the livestock industry, particularly the poultry sector, due to climate change-induced high ambient temperatures, heat stress (HS) has become a critical concern. HS disrupts the thermal balance in poultry, leading to detrimental effects on growth, immune function, and overall health. HSPs play a pivotal role in mitigating the impacts of HS in chickens. These molecular chaperones are involved in protein folding, unfolding, and assembly, and they are classified into several families based on their size, including small molecule HSPs, HSP40, HSP60, HSP70, HSP90, and HSP110. By maintaining cellular homeostasis and promoting stress tolerance, HSPs act as vital guardians in helping chickens cope with HS and its associated consequences. The review synthesized relevant literature to shed light on the importance of HSPs in stress adaptation, cellular homeostasis, and the maintenance of normal cell metabolism in chickens. The adverse effects of HS on chickens include oxidative stress and compromised immune systems, making them more susceptible to infections. So also, HS negatively affects production performance and meat quality in poultry. Understanding the functions of HSPs in chickens offers valuable insights into stress adaptation and health, and could potentially lead to the identification of HSP biomarkers, genetic selection for heat tolerance, investigations into the interplay between HSPs and immune function, and the development of nutritional interventions to enhance HSP activity. By exploring these potential research directions, the review aimed to contribute to the development of novel approaches to mitigate the negative effects of HS on poultry, ultimately improving productivity and animal welfare in a changing climate. |
| Kata kunci | Heat shock proteins, Stress Response, Heat Stress, Molecular Chaperons, Cellular Homeostasis, Immune Function |
| Pembimbing 1 | Prof. Dr. Ir. Elly Tugiyanti, M.P., IPU |
| Pembimbing 2 | Dr. Ir. Sri Rahayu, M.Si., IPU |
| Pembimbing 3 | |
| Tahun | 2024 |
| Jumlah Halaman | 8 |
| Tgl. Entri | 2024-02-13 11:31:33.696472 |