Artikel Ilmiah : I1J019022 a.n. SONYA HAELSA
| NIM | I1J019022 |
|---|---|
| Namamhs | SONYA HAELSA |
| Judul Artikel | The Effectiveness of Moringa (Moringa oleifera L.) and Gedi Leaves (Abelmoschus Manihot L.) Combination Towards Total Cholesterol Levels in Hypercholesterolemia induced Wistar rats (Rattus norvegicus) |
| Abstrak (Bhs. Indonesia) | Treating hypercholesterolemia can minimize the other cardiovascular disease. Treatment can be handled both medically or using traditional medicine. Substances contained in Moringa and Gedi leaves as a medical medicine can lowering total cholesterol. This research is a true experiment with pre-test and post-test designs. The samples were divided into 6 groups, namely group A (Positive control), group B (negative control), group C (80 mg/200gBw: 30 mg/200 gBW) group D (160 mg/200 gBW: 30 mg/200 gBW), group E (80 mg/200 gBW: 60mg/200 gBW) and group F control group with simvastatin. Experimental animals were given a HFD for 14 days and then given treatment according to the dose for 14 days. One Way ANOVA and Post-hoc Duncan were used to analyze the total cholesterol level data. All treatment groups can reduce total cholesterol levels. Group C can reduce with an average difference of 139.5, Group D =123.5, Group E = 125.75 and Group F = 92.75 The result showed that group C (1:1) has the most effective effect on decreasing total cholesterol level by with the smallest and optimal dose that can lower cholesterol levels the most |
| Abtrak (Bhs. Inggris) | Treating hypercholesterolemia can minimize the other cardiovascular disease. Treatment can be handled both medically or using traditional medicine. Substances contained in Moringa and Gedi leaves as a medical medicine can lowering total cholesterol. This research is a true experiment with pre-test and post-test designs. The samples were divided into 6 groups, namely group A (Positive control), group B (negative control), group C (80 mg/200gBw: 30 mg/200 gBW) group D (160 mg/200 gBW: 30 mg/200 gBW), group E (80 mg/200 gBW: 60mg/200 gBW) and group F control group with simvastatin. Experimental animals were given a HFD for 14 days and then given treatment according to the dose for 14 days. One Way ANOVA and Post-hoc Duncan were used to analyze the total cholesterol level data. All treatment groups can reduce total cholesterol levels. Group C can reduce with an average difference of 139.5, Group D =123.5, Group E = 125.75 and Group F = 92.75 The result showed that group C (1:1) has the most effective effect on decreasing total cholesterol level by with the smallest and optimal dose that can lower cholesterol levels the most |
| Kata kunci | Moringa Leaf, Gedi leaf, High Fat Diet (HFD), Hypercholesterolemia, Simvastatin |
| Pembimbing 1 | Prof. Dr. Saryono, S.Kep., M.Kes |
| Pembimbing 2 | Prof. Dr. Dra. Hernayanti, M.Si |
| Pembimbing 3 | |
| Tahun | 2023 |
| Jumlah Halaman | 10 |
| Tgl. Entri | 2023-02-13 16:32:25.779399 |