| NIM | I1C016007 |
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| Namamhs | KINTAN MELINDA |
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| Judul Artikel | Formulasi dan Evaluasi Lotion Minyak Atsiri Bunga Cengkeh (Syzygium aromaticum L.) Menggunakan Emulgator Triethanolamine dan Asam Stearat |
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| Abstrak (Bhs. Indonesia) | Minyak atsiri bunga cengkeh sangat potensial untuk dikembangkan menjadi suatu sediaan farmasi yaitu lotion. Sifat fisik dan stabilitas lotion sangat dipengaruhi oleh emulgator. Sehingga perlu dilakukan penelitian untuk melihat pengaruh kombinasi trietanolamin (TEA) dan asam stearat sebagai emulgator terhadap sifat fisik sediaan lotion. Sediaan lotion dibuat dalam 3 formula dengan perbandingan konsentrasi asam stearat dan trietanolamin yang berbeda (6%:2%, 5%:3%, dan 4%:4%), selanjutnya sediaan diuji organoleptis, homogenitas, daya sebar, daya lekat, pH, viskositas, uji stabilitas fisik metode freeze thaw. Konsentrasi asam stearat berbanding lurus dengan viskositas dan daya lekat, namun berbanding terbalik dengan daya sebar dan nilai pH. Sebaliknya, konsentrasi trietanolamin berbanding lurus terhadap pH dan daya sebar, namun berbanding terbalik terhadap viskositas dan daya lekat. Konsentrasi kombinasi asam stearat dan trietanolamin (TEA) yang menghasilkan formula lotion minyak bunga cengkeh paling baik yaitu asam stearat 6%: trietanolamin 2%. |
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| Abtrak (Bhs. Inggris) | Clove bud oil has the potential to be developed into a pharmaceutical preparation namely lotion. The physical properties and stability of the lotion are greatly influenced by the emulgator. So it is necessary to do research to see the effect of the combination of triethanolamine (TEA) and stearic acid as an emulgator on the physical properties of the lotion preparation. The lotion is made in 3 formulas with different concentrations of stearic acid and triethanolamine (6%: 2%, 5%: 3%, and 4%: 4%), then the preparation is tested for organoleptic, homogeneity, dispersibility, power adhesion, pH, viscosity, physical stability test by freeze thaw method. The concentration of stearic acid is directly proportional to viscosity and adhesion, but is inversely proportional to the dispersion power and pH value. On the other hand, triethanolamine concentration is directly proportional to pH and dispersive power, but is inversely related to viscosity and adhesion. The combination concentration of stearic acid and triethanolamine (TEA) that produces the best clove bud oil lotion formula is 6% stearic acid: 2% triethanolamine. |
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| Kata kunci | Lotion, Clove Bud Oil, Asam stearat, Trietanolamin (TEA). |
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| Pembimbing 1 | Dr. apt. Tuti Sri Suhesti, M.Sc |
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| Pembimbing 2 | Dr. apt. Eka Prasasti Nur Rachmani, M.Sc |
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| Pembimbing 3 | |
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| Tahun | 2020 |
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| Jumlah Halaman | 12 |
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| Tgl. Entri | 2020-11-16 15:17:17.33495 |
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