Artikel Ilmiah : G1G011036 a.n. ARIF ROMADHONA SETIAWAN
| NIM | G1G011036 |
|---|---|
| Namamhs | ARIF ROMADHONA SETIAWAN |
| Judul Artikel | PENGARUH PEMBERIAN DIET PROTEIN TERHADAP KADAR KALSIUM TULANG ALVEOLAR MANDIBULA ANAK TIKUS Rattus norvegicus GALUR WISTAR YANG MENGALAMI GANGGUAN KALSIFIKASI |
| Abstrak (Bhs. Indonesia) | Tumbuh kembang tulang memegang peranan penting dalam bidang kedokteran gigi anak karena akan menentukan status kematangan tulang. Kematangan tulang terjadi karena kalsifikasi tulang. Proses kalsifikasi tulang dipengaruhi oleh beberapa faktor salah satunya yaitu nutrisi. Protein merupakan salah satu nutrisi yang berperan dalam proses kalsifikasi tulang. Tujuan penelitian ini untuk mengetahui pengaruh pemberian diet protein terhadap kadar kalsium tulang alveolar mandibula anak tikus Rattus norvegicus galur Wistar yang mengalami gangguan kalsifikasi. Jenis penelitian ini merupakan eksperimental laboratoris dengan rancangan post-test only control group design. Sebanyak 24 sampel yang diberi makanan AD II dibagi menjadi empat kelompok yaitu satu kelompok kontrol (diberi diet protein standar) dan tiga kelompok perlakuan, tikus dengan gangguan kalsifikasi yang diberi diet protein rendah, diet protein standar dan diet protein tinggi. Subjek penelitian yaitu anak tikus Rattus norvegicus galur Wistar yang mengalami gangguan kalsifikasi dengan unit analisis yaitu tikus yang berusia 50 hari. Sampel penelitian berupa tulang alveolar mandibula dan dilakukan pengukuran kadar kalsium menggunakan spektrofotometri serapan atom. Data dianalisis menggunakan uji One Way ANOVA dan dilanjutkan dengan uji Post-Hoc LSD. Hasil penelitian menunjukkan kadar kalsium tulang alveolar mandibula masing-masing kelompok yaitu K: 14,468%, P1: 8,306%, P2: 13,443% dan P3: 19,12%. Diet protein dapat meningkatkan kadar kalsium tulang alveolar yang mengalami gangguan kalsifikasi (p<0,05). Diet standar protein lebih baik dalam meningkatkan kadar kalsium tulang alveolar dari pada diet rendah dan diet tinggi protein. Simpulan penelitian ini yaitu pemberian diet protein berpengaruh terhadap kadar kalsium tulang alveolar mandibula anak tikus Rattus norvegicus galur Wistar yang mengalami gangguan kalsifikasi. |
| Abtrak (Bhs. Inggris) | Bone growth plays an important role in pediatric dentistry because it will determine bone maturity. Maturity of the bone occured because of bone calcification. Bone calcification influenced by several factors one of them is nutrients. Protein is one of nutrients participate in the bone calcification. The aim of this research is to understand the effect of protein diet on calcium level of mandibular alveolar bone of Rattus norvegicus Wistar strain mice with calcification disorder. This research was an experimental laboratory research with a post-test only control group design. A total of 24 samples fed AD II were divided into four groups, a control group that were given standard protein diet and three treatment groups, mice with calcification disorders were treated using low, standard and high protein diet. The subject of the study was the mice of the Rattus norvegicus Wistar strain with calcification disorder and the analysis unit was 50 days old mice. The sample of the study was mandibular alveolar bone and calcium level was measured using atomic-absorption spectophotometry. Data analyzed using one way ANOVA test and followed by Post-Hoc LSD test. The results showed calcium level of mandibular alveolar bone were group K: 14,468%, P1: 8,306%, P2: 13,443% and P3: 19,123%. Protein diet could increase calcium level of alveolar bone with calcification disorder (p<0,05). Standard protein diet was better than low and high protein diet in increasing calcium level of alveolar bone. The conclusion is protein diet can effect on calcium level of mandibular alveolar bone of Rattus norvegicus Wistar strain mice with calcifcation disorder. |
| Kata kunci | Diet protein, tulang alveolar, kadar kalsium tulang, Rattus norvegicus galur Wistar, SSA |
| Pembimbing 1 | Dr. drg. A. Haris Budi W., M. Kes., A.P., S.IP., S.E. |
| Pembimbing 2 | Dr. Saryono, S.Kp., M. Kes. |
| Pembimbing 3 | |
| Tahun | 2017 |
| Jumlah Halaman | 17 |
| Tgl. Entri | 2017-07-22 09:44:08.036226 |