Artikel Ilmiah : G1A013133 a.n. DIVA AUGUSTI DIRGAHAYU
| NIM | G1A013133 |
|---|---|
| Namamhs | DIVA AUGUSTI DIRGAHAYU |
| Judul Artikel | HUBUNGAN USIA DAN JUMLAH PARITAS DENGAN GRADING KARSINOMA PAYUDARA DUKTAL INVASIF DI RSUD MARGONO SOEKARJO TAHUN 2015 |
| Abstrak (Bhs. Indonesia) | HUBUNGAN USIA DAN JUMLAH PARITAS DENGAN GRADING KARSINOMA PAYUDARA DUKTAL INVASIF DI RSUD MARGONO SOEKARJO TAHUN 2015 Diva Augusti Dirgahayu1, Hidayat Sulistyo2, Yudhi Wibowo3 1Jurusan Kedokteran Fakultas Kedokteran Universitas Jenderal Soedirman2 Bagian Ilmu Patologi Anatomi, RSUD Prof. Dr. Margono Soekarjo Purwokerto 3Patologi Anatomi, Universitas Jenderal Soedirman ABSTRAK Latar Belakang: Kanker payudara saat ini mengalami peningkatan insidensi relatif tinggi dari seluruh penyakit keganasan pada wanita. Karsinoma payudara duktal invasif merupakan salah satu jenis kanker payudara yang paling banyak ditemukan. Faktor risiko yang berpengaruh terhadap kejadian kanker payudara diantaranya usia dan jumlah paritas. Karsinoma payudara duktal invasif pada usia muda berhubungan dengan sifat tumor yang lebih agresif. Sedangkan wanita nulipara cenderung memiliki risiko lebih tinggi untuk terkena kanker payudara, namun belum diketahui pengaruhnya dengan grading histopatologi. Tujuan: Tujuan penelitian ini untuk mengetahui hubungan usia dan jumlah paritas dengan grading karsinoma payudara duktal invasif. Metode: Rancangan penelitian yang digunakan adalah analitik observasional dengan studi cross sectional. Pengambilan data sekunder dari rekam medis dan hasil pemeriksaan patologi anatomi di RSUD Margono Soekarjo didapatkan 44 sampel. Analisis bivariat menggunakan uji chi square yang direkategorik. Hasil: Didapatkan hasil pada usia <50 tahun pasien grade 1-2 sebanyak 13 orang (56,5%), grade 3 sebanyak 10 orang (43,5%). Usia ≥50 tahun pasien grade 1-2 sebanyak 8 orang (38,1%), grade 3 sebanyak 13 orang (61,9%). Wanita kelompok nulipara-primipara sebanyak 5 orang (45,5%) menderita grade 1-2, pada grade 3 sebanyak 6 orang (54,5%). Kelompok multipara-grandemultipara 16 orang (48,5%) menderita grade 1-2, sedangkan grade 3 sebanyak 17 orang (51,5%). Kesimpulan: Hasil analisis statistik menunjukkan tidak terdapat hubungan bermakna antara usia dengan grading karsinoma payudara duktal invasif, nilai p = 0,222 dan tidak terdapat hubungan antara jumlah paritas dengan grading karsinoma payudara duktal invasif, nilai p = 0,862 Kata Kunci : grading karsinoma duktal invasif, usia, jumlah paritas |
| Abtrak (Bhs. Inggris) | ASSOCIATION OF AGE AND PARITY WITH INVASIF DUCTAL BREAST CARCINOMA GRADING IN MARGONO SOEKARJO HOSPITAL AT 2015 Diva Augusti Dirgahayu1, Hidayat Sulistyo2, Yudhi Wibowo3 1Department of Medicine, Faculty of Medicine, Jenderal Soedirman University2 Section of Pathology Anatomy, Prof. Dr. Margono Soekarjo Purwokerto Hospital 3Pathology Anatomy, Jenderal Soedirman University ABSTRAK Background: Breast cancer is currently experiencing a relatively high increase in the incidence of all malignancies in women. Invasive ductal carcinoma of the breast is one of the most commonly found types of breast cancer. The risk factors that affect the incidence of breast cancer include age and parity. Invasive ductal breast carcinoma at a young age is associated with more aggressive tumor characteristics. While nulliparous women tend to have a higher risk for developing breast cancer, its effect is not yet known with histopathological grading. Goals: The purpose of this study was to determine the relationship between age and parity with invasive ductal breast carcinoma grading. Methods: The design of the study was observational analytic with cross sectional study. Samples obtained from collection of secondary data from medical records and anatomic pathology test results in Margono Soekarjo Hospital were 44 samples. Bivariate analysis using recategorized chi square test.. Results: The results obtained from patients age <50 years there were 13 people (56.5%) in grade 1-2 and 10 people (43.5%) in grade 3. Among patients age ≥50 years, 8 people (38.1%) were in grade 1-2 and 13 people (61.9%) were in grade 3. In nullipara-primipara group of women, 5 people (45.5%) had grade 1-2, and 6 people (54.5%) were in grade 3. In multipara-grandemultipara group of women, 16 people (48.5%) were in grad 1-2, while 17 people (51.5%) were in grade 3. Conclusion: Statistical analysis showed no significant relationship between age and invasive ductal breast carcinoma grading (p = 0.222) and there was no correlation between the number of parity and invasive ductal breast carcinoma grading (p = 0.862). Keywords : invasive ductal carcinoma grade, age, parity |
| Kata kunci | Kata Kunci : grading karsinoma duktal invasif, usia, jumlah paritas |
| Pembimbing 1 | dr. Hidayat Sulistyo, Sp.PA, Msi.Med |
| Pembimbing 2 | dr. Yudhi Wibowo, MPH |
| Pembimbing 3 | Diva Augusti Dirgahayu |
| Tahun | 2016 |
| Jumlah Halaman | 1 |
| Tgl. Entri | 2017-02-08 13:46:08.379172 |