Update Artikelilmiah: 46987

WENSESLAUS KOSTRADILO DASEPTA

NIM

Judul Artikel

Abstrak (Bhs. Indonesia)

Latar belakang: Karsinoma mammae merupakan penyakit karsinoma dengan persentase 
kasus baru tertinggi, yaitu sebesar 43,3% dan persentase kematian akibat karsinoma 
mammae sebesar 12,9% di dunia,Di indonesia jumlah kematiannya mencapai lebih 
dari 22 ribu jiwa. Faktor risiko nya antara lain : usia, usia menarche, jumlah paritas dan 
riwayat kontrasepsi hormonal.
Tujuan: Tujuan umum penelitian ini adalah untuk mengetahui hubungan antara usia, usia 
menarche, jumlah paritas dan riwayat kontrasepsi hormonal dengan grading histopatologi 
pada pasien karsinoma mammae di RSUD Prof. Dr. Margono Soekarjo.
Metode: Rancangan penelitian yang digunakan pada penelitian ini adalah penelitian analitik 
observasional dengan pendekatan cross sectional, Pengambilan data 
secara retrospektif terhadap data sekunder berupa catatan rekam medik pasien terdiagnosis 
karsinoma mammae yang tercatat di RSUD Prof. Dr. Margono Soekarjo pada tahun 2019-
2023. Data dianalisis dengan uji chi-square.
Hasil: Dari 120 responden,paling banyak pada rentang usia ≥40 tahun, yaitu sebanyak 106 
orang (88,3%).berdasarkan grading diklasifikasikan menjadi 3 kelompok, yakni grade I, II, 
III. Grade I sebanyak 22 (18,3%), Grade II sebanyak 27 (22,5%), dan Grade III sebanyak 71 
(59,2%). Hasil uji Chi square karakteristik pasien menunjukkan bahwa terdapat hubungan 
yang signifikan (p value 0,000) antara usia pasien dengan grading histopatologi pasien 
karsinoma mammae. Hasil uji Chi square karakteristik pasien menunjukkan bahwa tidak 
terdapat hubungan yang signifikan (p value 0,342) antara usia menarche pasien dengan 
grading histopatologi pasien Karsinoma mammae. Hasil uji Chi square karakteristik pasien 
menunjukkan bahwa tidak terdapat hubungan yang signifikan (p value = 0,784) antara jumlah 
paritas pasien dengan grading histopatologi pasien Karsinoma mammae. Hasil uji Chi square 
karakteristik pasien menunjukkan bahwa tidak terdapat hubungan yang signifikan (0,196) 
antara riwayat kontrasepsi pasien dengan grading histopatologi pasien Karsinoma mammae.
Kesimpulan: Terdapat hubungan yang signifikan antara usia dengan grading histopatologi 
pasien karsinoma mammae.

Abtrak (Bhs. Inggris)

Background: Mammary carcinoma is a carcinoma disease with the highest percentage of new cases, 
which is 43.3% and the percentage of deaths due to mammary carcinoma is 12.9% in the world. The 
incidence of mammary carcinoma in the world is relatively high at 20% of all malignancies. In Indonesia 
the number of deaths reaches more than 22 thousand people. The incidence of mammary carcinoma in 
the world is relatively high at 20% of all malignancies. Risk factors include: age, age of menarche, 
number of parities and history of hormonal contraception.
Objectives: The general objective of this study was to determine the relationship between age, age of 
menarche, number of parities and history of hormonal contraceptives with histopathological features in 
patients with mammary carcinoma at RSUD Margono Soekardjo.
Methods: The research design used in this study was observational analytic research with a cross 
sectional approach, namely by collecting data at one time without any follow-up of the research sample). 
Data were collected retrospectively from secondary data in the form of medical records of patients 
diagnosed with mammary carcinoma recorded at RSUD Margono Soekardjo Data were analyzed using 
the chi-square test.
Results: Of the 120 respondents, most were in the age range ≥40 years, as many as 106 people (88.3%). 
based on grading classified into 3 groups, namely grade I, II, III. Grade I was 22 (18.3%), Grade II was 
27 (22.5%), and Grade III was 71 (59.2%). The results of the Chi square test of patient characteristics 
show that there is a significant relationship (p value 0.000) between patient age and histopathological 
grading of mammary carcinoma patients. The results of the Chi square test of patient characteristics 
show that there is no significant relationship (p value 0.342) between the age of menarche of patients 
with histopathological grading of mammary carcinoma patients. The results of the Chi square test of 
patient characteristics show that there is no significant relationship (p value = 0.784) between the 
number of patient parities and the histopathological grading of mammary carcinoma patients. The 
results of the Chi square test of patient characteristics show that there is no significant relationship 
(0.196) between the patient's contraceptive history and the histopathological grading of mammary 
carcinoma patients.
Conclusion: There is a significant relationship between age and histopathologic features of mammary 
carcinoma patients.

Kata kunci

Pembimbing 1

Pembimbing 2

Pembimbing 3

Tahun

Jumlah Halaman