Update Artikelilmiah: 41078

INDAH FADLILLAH

NIM

Judul Artikel

Abstrak (Bhs. Indonesia)

Obesitas meningkatan massa lemak dan asam lemak bebas yang berdampak pada diabetes melitus tipe 2 (DMT-2). DMT-2 ditandai dengan gula darah tinggi (hiperglikemia). Hiperglikemia memicu peningkatan kadar LDL hingga berujung pada berbagai komplikasi penyakit. Penelitian ini dilakukan untuk mengetahui pengaruh pemberian yogurt kecambah kacang koro pedang putih plus ekstrak kayu manis (yocaroma) terhadap kadar gula darah dan LDL penderita DMT-2 obsesitas. Penelitian true experimental ini menggunakan prepost test control group design. Subjek penelitian yaitu wanita berusia 40-70 tahun, IMT>25 kg/m2, GDP>126 mg/dL, dan LDL>100 mg/dL di Desa Purwosari. Subjek berjumlah 19 orang, kelompok yocaroma 10 orang dan plasebo 9 orang. Yogurt 200 mL/hari diantarkan ke rumah subjek setiap pagi pukul 06.00-08.00 selama 2 bulan.  Kadar gula darah dan LDL diperiksa sebelum dan setelah intervensi. Recall konsumsi subjek dilakukan 4 kali. Analisis data, khususnya kadar GDP menggunakan paired t-test dan wilcoxon, untuk kadar LDL menggunakan paired t-test. Subjek penelitian bersifat homogen (p>0,05). Yocaroma signifikan menurunkan GDP dari 188 mg/dL menjadi 139,6 mg/dL (p=0,002), dan LDL dari 165,10 mg/dL menjadi 128,25 mg/dL (p=0,000). Konsumsi yocaroma bermanfaat untuk mencegah komplikasi DMT-2 pada obesitas, dengan cara menurunkan kadar GDP dan LDL.

Abtrak (Bhs. Inggris)

Obesity increase free fatty acids which impact on type 2 diabetes mellitus (T2DM). T2DM characterized by high blood glucose levels (hyperglycemia). Hyperglycemia increase LDL levels, which can lead various disease complications. The purpose of this study to determine effect of giving jack bean sprouts plus cinnamon extract yogurt (yocaroma) on blood sugar and LDL levels in obese T2DM patients. This experimental study used prepost test control group design. Subjects were 40-70 years old Purwosari Village women, BMI>25 kg/m2, GDP>126 mg/dL, and LDL>100 mg/dL. Subjects were 19 people, 10 people were yocaroma and 9 people were placebo. 200 mL/day yogurt delivered to subject's house every morning at 06.00-08.00 for 2 months. Subjects were examined fasting blood glucose (FBG) levels and LDL before and after intervention. The subject's dietary was monitored using a 4x24-h dietary recall. FBG was analyzed by paired t-test and wilcoxon, LDL was analyzed by paired t-test. Subjects were homogeneous (p>0,05), 200 mL/day yocaroma for 2 months reduced FBG from 188 mg/dL to 139,6 mg/dL (p=0,002) and LDL from 165,10 mg/dL to 128,25 mg/dL (p=0,000). Yocaroma can preventing complication of T2DM in obesity by reducing FBG and LDL levels.

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