Update Artikelilmiah: 37005

FATHI TSAMARA GHUFROON RIFAI

NIM

Judul Artikel

Abstrak (Bhs. Indonesia)

Pendahuluan: Obesitas dapat menyebabkan pengeluaran sitokin pro-inflamasi yaitu interleukin-6. IL-6 dapat menjadi faktor penyebab komplikasi dari obesitas yaitu resistensi insulin. Latihan fisik dinilai dapat digunakan untuk menangani obesitas dan dapat menurunkan kadar Interleukin-6 (IL-6). Model latihan fisik yang bisa digunakan adalah Moderate Intensity Continuous Training (MICT).Tujuan: Mengetahui pengaruh program intervensi MICT terhadap kadar IL-6 pada wanita obesitas. Metode: Penelitian ini menggunakan merupakan jenis penelitian observasional cross sectional analisis data sekunder. Subjek sebanyak 14 wanita obesitas. Setiap subyek melakukan intervensi MICT selama 12 minggu dengan frekuensi 3 kali setiap minggu. Pemeriksaan IL-6 diukur sebelum dan setelah intervensi menggunakan kit Elisa dengan metode Sandwich. Data dianalisis secara univariat dan bivariat. Hasil: Hasil menunjukkan kadar IL-6 sebelum intervensi sebesar 4,02 ± 0,64 pg/ml. Kadar IL-6 post-intervensi sebesar 2,63 ± 0,75 pg/ml. Hasil uji t-berpasangan menunjukkan adanya perbedaan yang signifikan (p=0,000). Kesimpulan: Terdapat peningkatan massa otot sebelum dan sesudah latihan baik pada latihan fisik HIIT maupun MICT. HIIT dan MICT sama efektif dalam meningkatkan massa otot.

Abtrak (Bhs. Inggris)

Introduction: Obesity causes the release of pro-inflammatory cytokines was interleukin-6. IL-6 can be a factor causing complications of obesity was insulin resistance. Physical exercise was considered to be used to treat obesity and can reduce levels of Interleukin-6 (IL-6). The physical exercise model that can be used is Moderate Intensity Continuous Training (MICT). Objective:  to determine the effect of the MICT intervention program on IL-6 levels in obese women. Methods: This study used an observational cross-sectional type of secondary data analysis. Subjects were 14 obese women. Each subject intervened MICT for 12 weeks with a frequency of 3 times every week. IL-6 assays were measured before and after the intervention using the Elisa kit with the Sandwich method. Data were analyzed by univariate and bivariate. . Results: The results showed that IL-6 levels before intervention were 4.02 ± 0.64 pg/ml. Post-intervention IL-6 levels were 2.63 ± 0.75 pg/ml. Paired t-test results showed a significant difference (p=0.000). Conclusion: MICT affect IL-6 levels of obese women, MICT can reduced IL-6 levels of obese women.

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