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Abstrak (Bhs. Indonesia)

Latar Belakang: Insiden mioma uteri sekitar 20% -35% dari seluruh wanita di dunia yang mana 50-70% kasus menyerang wanita pada usia reproduksi. Keterlibatan hormon estrogen yang dimediasi oleh ikatan dengan reseptornya merupakan promoter utama pertumbuhan mioma uteri. Pemeriksaan imunohistokomia pada pasien hiperplasia endometrium ditemukan lapisan endometrium dan sel otot polos tumor yang imunoreaktif terhadap reseptor estrogen. Pada beberapa laporan kasus ditemukan terjadinya mioma uteri dan hiperplasia endometrium secara bersamaan.
Tujuan : Untuk mengetahui hubungan usia dan hiperplasia endometrium pada pasien terdiagnosa mioma uteri pasca operasi berdasarkan rekam medik di SMF Patologi Anatomi RSUD Prof. Dr. Margono Soekardjo Purwokerto
Metode : Merupakan penelitian analitik observasional dengan pendekatan cross-sectional pada sampel data rekam medik pasien yang dilakukan pemeriksaan histo-PA pasca operasi di Laboratorium Patologi Anatomi RSUD Prof. Dr. Margono Soekarjo Purwokerto dengan diagnosis klinis mioma uteri dan/atau mioma uteri dengan hiperplasia endometrium dalam kurun waktu 2017 – 2019 secara total sampling.
Hasil dan Pembahasan : Berdasarkan 385 data sampel, peneliti menemukan terdapat 306 kasus mioma uteri dan 79 kasus mioma uteri dengan hiperplasia endometrium. Persebaran data usia pasien mioma uteri menurut dekade usia diurutkan sebagai berikut; dekade usia 5 (41 – 50 tahun) sebesar 54,03% dekade 4 (31 – 40 tahun) sebesar 24,68% , dan dekade 6 (51 – 60 tahun) sebesar 14,28%. Selanjutnya diikuti oleh dekade 3 (21 – 30 tahun) sebesar 4,41% dan dekade 7 (61 – 70 tahun) sebesar 2,59%. Tidak terdapat penderita mioma uteri yang berusia dekade 1 dan 2. Distribusi usia pada pasien mioma uteri lebih luas dibandingkan dengan pasien mioma uteri dengan hiperplasia endometrium
Kesimpulan : Dekade usia pasien mioma uteri terbanyak adalah dekade usia 5 (41 – 50 tahun). Terdapat perbedaan yang bermakna pada rerata usia pasien mioma uteri dengan mioma uteri disertai hiperplasia endometrium.

Abtrak (Bhs. Inggris)

Background: The incidence of uterine myoma is around 20% -35% of all women in the world where 50-70% of cases attack women of reproductive age. The involvement of estrogen by binding to its receptors is the main promoter of the growth of uterine myoma. Immunohistochemistry examination in patients with endometrial hyperplasia find endometrial lining and tumor smooth muscle cells that were immunoreactive against estrogen receptors.  Uterine myoma and endometrial hyperplasia are found simultaneously in several case reports.
Aim : To determine the relationship between age and endometrial hyperplasia in postoperative uterine myoma patients based on medical records at the Pathology Anatomy department of Prof. Dr. Margono Soekarjo Purwokerto General Hospital 
Method : The study was conducted using observational analytic study with a cross-sectional approach to a sample of postoperative uterine myoma patients based on medical records at the Pathology Anatomy department of Prof. Dr. Margono Soekarjo Purwokerto General Hospital  with a clinical diagnosis of uterine myoma and / or uterine myoma with endometrial hyperplasia in the period 2017 - 2019 in total sampling.
Result and Discussion : The research found that there were 306 cases of uterine myoma and 79 cases of uterine myoma with endometrial hyperplasia of 385 of total cases. The distribution of data on the age of uterine myoma patients according to the age decade is sorted as follows; decade of age 5 (41 - 50 years) amounted to 54.03% in decade-4 (31 - 40 years) by 24.68%, and decade-6 (51 - 60 years) by 14.28%. Followed by decade-3 (21 - 30 years) at 4.41% and decade-7 (61 - 70 years) at 2.59%. There are no uterine myoma patients aged 1 and 2 decades.The age distribution in uterine myoma patients is wider than in uterine myoma patients with endometrial hyperplasia
Conclusion : Most of the patients with uterine myoma were in the decade of age 5 (41-50 years). There is a significant difference in the mean age of uterine myoma patients with uterine myoma accompanied by endometrial hyperplasia.

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