Update Artikelilmiah: 15179

GLORIA ANIMALESTO

NIM

Judul Artikel

Abstrak (Bhs. Indonesia)

Filariasis limfatik atau kaki gajah merupakan suatu penyakit infektif yang menyerang sistem limfa dan disebabkan oleh cacing filaria. Cacing filaria penyebab filariasis limfatik yaitu Wuchereria bancrofti, Brugia malayi, dan B. timori. Hampir seluruh Indonesia merupakan daerah endemis filariasis limfatik. Kabupaten Sumba Barat Daya merupakan salah satu daerah endemis filariasis limfatik dengan prevalensi 1,16%. Desa Karang Inda adalah desa yang diketahui memiliki kasus kronis filariasis limfatik, namun belum dilaksanakan program pengobatan massal. Prevalensi di desa ini juga belum diketahui nilainya sehingga diperlukan adanya survei untuk mengetahui nilai mikrofilaria (mf rate).
Penelitian ini bertujuan untuk mengetahui prevalensi infeksi filariasis limfatik dengan metode mikroskopik, mengetahui prevalensi infeksi filariasis limfatik dengan metode deteksi antigen ICT, serta mengetahui sensitivitas dan spesifisitas ICT dalam uji diagnostik filariasis limfatik secara mikroskopik. Rancangan penelitian yang digunakan adalah observasi analitik dengan studi seran lintang (cross-sectional).
Hasil pemeriksaan menunjukkan prevalensi infeksi filariasis limfatik secara mikroskopik dan ICT yaitu 3,36% dan 3,47%. Sensitifitas dan spesifisitas ICT terhitung tinggi yaitu 90% dan 94,96%.

Abtrak (Bhs. Inggris)

Lymphatic filariasis (LF), known as elephantiasis, is a  mosquito-borne parasitic disease caused by the nematode parasites such as Wuchereria bancrofti, Brugia malayi, and Brugia timori. One among the endemic areas in Indonesia is Southwest Sumba district which its prevalence of 1,16%. Of this district, the Karang Inda village has a characteristic of chronic filariasis, but unfortunately it has never been being chosen for implementation of mass drug administration (MDA) yet. This might probably due to the rate of filariasis in this area is still unknown. Determination of microfilaria rate in this area then became prerequisite to be done.
This research was aimed to determine lymphatic filariasis infection prevalence by applying microscopic method, determine lymphatic filariasis infection prevalence applying  antigen detection of Immunochromatographic Test (ICT), and determine sensitivity and specificity of ICT in microscopic examination of lymphatic filariasis diagnostic test. This research was applying analytical observation and cross sectional study as its design.
The data showed the infection lymphatic filariasis prevalence by microscopic and ICT was 3,36% and 3.47%, respectively. The difference of these prevalence is caused by mix infection between W. bancrofti and B. timori in this village. Sensitivity and specificity of ICT comparatively high, they are 90% and 94,96%.

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