Update Artikelilmiah: 11029

DINA NURMALA SARI

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Abstrak (Bhs. Indonesia)

Latar Belakang : Wortel (Daucus carota) dan Daun teh (Camellia sinensis) sudah dikenal masyarakat dan digunakan untuk kebutuhan sehari-hari salah satunya sebagai tanaman obat yang berpotensi menimbulkan efek diuresis. Wortel mengandung kumarin glikosid dan flavonoid dan daun teh mengandung teobromin, teofilin, dan kafein yang diduga menimbulkan efek diuresis.
Tujuan : Mengetahui efek diuresis campuran sari umbi wortel (Daucus carota) dan seduhan daun teh (Camellia sinensis) pada tikus putih jantan jenis wistar 
Metode : Penelitian eksperimental dengan post test only with control group design. Tikus putih jantan (30 ekor) dibagi dalam 5 kelompok. Kelompok A (aquades), kelompok B (furosemid), kelompok C (sari umbi wortel 15 % dan daun teh 300mg/kgBB) , kelompok D (sari umbi wortel 30 % dan daun teh 600mg/kgBB), dan kelompok E (sari umbi wortel 60 % dan daun teh 2400mg/kgBB). Volume urin tikus masing-masing kelompok ditampung dan diukur setiap jam selama 12 jam
Hasil : Hasil volume urin tikus selama 12 jam kelompok A 4.33 ml; kelompok B 15.39 ml; kelompok C 9.89 ml; kelompok D 13.14 ml; kelompok E 14.28 ml. Uji ANOVA menunjukkan perbedaan signifikan (p=0,000), dilanjutkan Post Hoc LSD menunjukkan perbedaan signifikan (p<0,05) antara kelompok A dengan kelompok  B, C, D dan E; kelompok B dengan kelompok A dan C.
Kesimpulan : Campuran sari umbi wortel dan seduhan daun teh mempunyai efek diuresis. Dosis efektif minimal campuran sari umbi wortel dan seduhan daun teh untuk menimbulkan efek diuresis adalah sari umbi wortel 60% dan daun teh 600mg/kgBB.

Abtrak (Bhs. Inggris)

Background : Carrot (Daucus carota) and tea leaf (Camellia sinensis) have been known and used for daily consumption. Carrot and tea leaf is being used as a herbal medicine that could potentially cause diuresis effect. Carrot contains coumarin glycoside and flavonoids. Tea leaf contains theobromine, theophylline, and caffeine. All of those substances are supposed to cause diuretic effect.
Objective: Identify the diuretic effect by combination of carrot (Daucus carota) and infusion tea leaf (Camellia sinensis) in male wistar rats.
Methods: This is an experimental research with post test only (with) control group design. Male wistar rats (30 animals) were divided into 5 groups. Group A (aquades), group B (furosemide), group C (15% of carrot and leaf tea 300mg/kgBB), group D (30% of carrot and tea leaf 600mg/kgBB), and group E (60% of carrot and tea leaf 2400mg/kgBB). Urine samples were collected every hour for 12 hour to be measured in volume. 
Results: The result showed the urine volume during the 12 hours of group A 4.33 ml; group B 15.39 ml; group C 9.89 ml; group D 13.14 ml; group E 14.28 ml. Statistical analysis using ANOVA showed a significant difference (p = 0.000), followed by Post Hoc LSD which showed significant differences in  (p <0.05) between group A and group B, C, D and E; group B with group A and C.
Conclusion: The combination of carrot and tea leaf has diuretic effect. The minimum effective dose to induce diuretic effect is 60% of carrot and tea leaf in 600 mg/kgBB

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